ArticleFrontiers in plant science2015
Promotion of flavonoid biosynthesis in leaves and calli of ornamental crabapple (Malus sp.) by high carbon to nitrogen ratios.
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Integrated Analysis of Transcriptome and Metabolome Reveals the Accumulation of Anthocyanins in Black Soybean (Plants (Basel, Switzerland) · 2025Article
- Multiscale physiological responses to nitrogen supplementation of maize hybrids.Plant physiology · 2024Article
- The RNA Directed DNA Methylation (RdDM) Pathway Regulates Anthocyanin Biosynthesis in Crabapple (Plants (Basel, Switzerland) · 2021Article
- Preliminary Study on the Effect of Nitrogen Fertilisation on Phytochemical Content Quality ofTropical life sciences research · 2021Article
- Gibberellins Inhibit Flavonoid Biosynthesis and Promote Nitrogen Metabolism inInternational journal of molecular sciences · 2021Article
- Seasonal dynamics of the phenolic constituents of the cones and leaves of orientalRSC advances · 2021Article
- Chlorophyll a Fluorescence Transient and 2-Dimensional Electrophoresis Analyses Reveal Response Characteristics of Photosynthesis to Heat Stress inPlants (Basel, Switzerland) · 2020Article
- Flavonoids and Isoflavonoids Biosynthesis in the Model LegumePlants (Basel, Switzerland) · 2020Review
- A R2R3-MYB gene-based marker for the non-darkening seed coat trait in pinto and cranberry beans (Phaseolus vulgaris L.) derived from 'Wit-rood boontje'.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
- Determination of Flavonoids and Carotenoids and Their Contributions to Various Colors of Rose Cultivars (Frontiers in plant science · 2019Article
- Differential expression of anthocyanin biosynthesis genes in3 Biotech · 2018Article
- Nitrogen form and mycorrhizal inoculation amount and timing affect flavonol biosynthesis in onion (Allium cepa L.).Mycorrhiza · 2018Article
- Global gene expression analysis of the response of physic nut (Jatropha curcas L.) to medium- and long-term nitrogen deficiency.PloS one · 2017Article
- Flavonoid Accumulation Plays an Important Role in the Rust Resistance ofFrontiers in plant science · 2017Article
- The Role of Flavonoids in Nodulation Host-Range Specificity: An Update.Plants (Basel, Switzerland) · 2016Review
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Flavonoids are secondary metabolites that play important roles in plant physiology. Despite numerous studies examined the effects of available carbon (C) or nitrogen (N) on flavonoid biosynthesis, the mechanism of C/N interactive effects on flavonoid metabolism is still unclear. In this study, we analyzed the composition of flavonoids and the expression levels of flavonoid-related genes in leaves and calli of crabapple (Malus sp.) cultivars with different leaf colors grown on media with different C/N ratios. Our results show that high C/N ratios induce anthocyanin pigmentation in leaves of the ever-red cultivar 'Royalty' and the spring-red cultivar 'Prairifire,' as well as in three types of calli derived from the ever-green cultivar 'Spring Snow,' but not in the leaves of the ever-green cultivar 'Flame.' This phenomenon therefore correlated with anthocyanin content in these different samples. In addition, high C/N ratios in the growth media resulted in an increase in the concentration of flavones and flavonols in the leaves of the three crabapple cultivars. The transcript levels of the general flavonoid pathway genes [from chalcone synthase (CHS) to uridine diphosphat-glucose: flavonoid 3-O-glycosyltransferase (UFGT) and flavonol synthase (FLS)] increased in response to high C/N ratios, and this in turn was correlated with the concentration of anthocyanins, flavones and flavonols in the leaves and calli. Expression of the late flavonoid/anthocyanin biosynthetic genes, anthocyanidin synthase (ANS), UFGT and FLS in particular, was more strongly influenced by C/N ratios than other structural genes, and the increased expression of the structural genes under high C/N ratios coincided with a coordinated increase in transcript levels of a MYB transcription factor, MYB10. These results are likely to be useful for future generation of plants with an optimized flavonoid/anthocyanin content or desirable organ coloration.
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