Evidence map›Paper›PMID 26388781›Full record

ReviewFrontiers in physiology2015

Animal models in peritoneal dialysis.

Olga Nikitidou, Vasiliki I Peppa, Konstantinos Leivaditis, Theodoros Eleftheriadis, Sotirios G Zarogiannis, Vassilios Liakopoulos

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Methods to Measure Water Permeability.Advances in experimental medicine and biology · 2023
    Article
  5. Article
  6. Experimental models in peritoneal dialysis (Review).Experimental and therapeutic medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Olga NikitidouDivision of Nephrology and Hypertension, 1st Department of Internal Medicine, School of Medicine, American Hellenic Educational Progressive Association Hospital, Aristotle University of Thessaloniki Thessaloniki, Greece.
Vasiliki I PeppaDepartment of Physiology, Faculty of Medicine, BIOPOLIS, University of Thessaly Larissa, Greece.
Konstantinos LeivaditisDivision of Nephrology and Hypertension, 1st Department of Internal Medicine, School of Medicine, American Hellenic Educational Progressive Association Hospital, Aristotle University of Thessaloniki Thessaloniki, Greece.
Theodoros EleftheriadisDivision of Nephrology and Hypertension, 1st Department of Internal Medicine, School of Medicine, American Hellenic Educational Progressive Association Hospital, Aristotle University of Thessaloniki Thessaloniki, Greece.
Sotirios G ZarogiannisDepartment of Physiology, Faculty of Medicine, BIOPOLIS, University of Thessaly Larissa, Greece.
Vassilios LiakopoulosDivision of Nephrology and Hypertension, 1st Department of Internal Medicine, School of Medicine, American Hellenic Educational Progressive Association Hospital, Aristotle University of Thessaloniki Thessaloniki, Greece.
Aristotle University of Thessaloniki · GRUniversity of Thessaly · GRAHEPA University Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritoneal dialysis (PD) has been extensively used over the past years as a method of kidney replacement therapy for patients with end stage renal disease (ESRD). In an attempt to better understand the properties of the peritoneal membrane and the mechanisms involved in major complications associated with PD, such as inflammation, peritonitis and peritoneal injury, both in vivo and ex vivo animal models have been used. The aim of the present review is to briefly describe the animal models that have been used, and comment on the main problems encountered while working with these models. Moreover, the differences characterizing these animal models, as well as, the differences with humans are highlighted. Finally, it is suggested that the use of standardized protocols is a necessity in order to take full advantage of animal models, extrapolate their results in humans, overcome the problems related to PD and help promote its use.

Indexed as

animal modelsion and water transportmembrane physiologyperitoneal dialysisussing chamber

Identifiers

PMID26388781
PMCPMC4555018
OpenAlexW1820466624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.