Evidence map›Paper›PMID 26386856›Full record

ArticleDigestive diseases and sciences2016

Race and Prevalence of Large Bowel Polyps Among the Low-Income and Uninsured in South Carolina.

Kristin Wallace, Heather M Brandt, James D Bearden, Bridgette F Blankenship, Renay Caldwell, James Dunn, Patricia Hegedus, Brenda J Hoffman, Courtney H Marsh, William H Marsh and 7 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Black-White disparities across the colorectal cancer care continuum in the USA.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  3. Racial Differences in Colorectal Adenomas at Screening Colonoscopy in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Observational
  4. Article
  5. Review
  6. Article
  7. Article
  8. Predictors of Incident Serrated Polyps: Results from a Large Multicenter Clinical Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Helicobacter pylori is associated with increased risk of serrated colonic polyps: Analysis of serrated polyp risk factors.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018
    Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Kristin WallaceHollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA. Wallack@musc.edu.ORCID http://orcid.org/0000-0002-4297-9064
Heather M BrandtCenter for Colon Cancer Research, University of South Carolina, Columbia, SC, USA.
James D BeardenGibbs Cancer Center and Research Institute, Spartanburg Regional Healthcare System, Spartanburg, SC, USA.
Bridgette F BlankenshipDepartment of Public Health Sciences, Medical University of South Carolina, 68 President Street, Charleston, SC, 29425, USA.
Renay CaldwellCenter for Colon Cancer Research, University of South Carolina, Columbia, SC, USA.
James DunnGibbs Cancer Center and Research Institute, Spartanburg Regional Healthcare System, Spartanburg, SC, USA.
Patricia HegedusGibbs Cancer Center and Research Institute, Spartanburg Regional Healthcare System, Spartanburg, SC, USA.
Brenda J HoffmanHollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
Courtney H MarshDepartment of Public Health Sciences, Medical University of South Carolina, 68 President Street, Charleston, SC, 29425, USA.
William H MarshHollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
Cathy L MelvinHollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
March E SeabrookCenter for Colon Cancer Research, University of South Carolina, Columbia, SC, USA.
Ronald E SterbaHollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
Mary Lou StinsonCenter for Colon Cancer Research, University of South Carolina, Columbia, SC, USA.
Annie ThibaultCenter for Colon Cancer Research, University of South Carolina, Columbia, SC, USA.
Franklin G BergerCenter for Colon Cancer Research, University of South Carolina, Columbia, SC, USA.
Anthony J AlbergHollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
Medical University of South Carolina · USUniversity of South Carolina · USSpartanburg Regional Healthcare System · US

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Jian Ouyang · 2009 to 2026
$42.7M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
SOUTH CAROLINA CLINICAL & TRANSLATIONAL RESEARCH INSTITUTE (SCTR)UL1RR029882 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2009 to 2011
$10.1M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR000062 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2012 to 2014
$9.4M
TISSUE BIOREPOSITORY COREP30GM103336 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BERGER, FRANKLIN G. · 2013 to 2017
$5.4M
Race, pathomolecular signature and colorectal cancer survivalK07CA151864 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI WALLACE, KRISTIN · 2011 to 2015
$649k
NCATS NIH HHS UL1 TR000062NCATS NIH HHS UL1 TR001450NCI NIH HHS K07 CA151864NCI NIH HHS K07CA151864-01A1NCI NIH HHS P30 CA138313NCRR NIH HHS UL1 RR029882NIGMS NIH HHS P30 GM103336NIGMS NIH HHS P30 GM103336-02
6 · The paper itself

Abstract

backgroundCompared to whites, blacks have higher colorectal cancer incidence and mortality rates and are at greater risk for early-onset disease. The reasons for this racial disparity are poorly understood, but one contributing factor could be differences in access to high-quality screening and medical care.

aimsThe present study was carried out to assess whether a racial difference in prevalence of large bowel polyps persists within a poor and uninsured population (n = 233, 124 blacks, 91 whites, 18 other) undergoing screening colonoscopy.

methodsEligible patients were uninsured, asymptomatic, had no personal history of colorectal neoplasia, and were between the ages 45-64 years (blacks) or 50-64 years (whites, other). We examined the prevalence of any adenoma (conventional, serrated) and then difference in adenoma/polyp type by race and age categories.

resultsPrevalence for ≥1 adenoma was 37 % (95 % CI 31-43 %) for all races combined and 36 % in blacks <50 years, 38 % in blacks ≥50 years, and 35 % in whites. When stratified by race, blacks had a higher prevalence of large conventional proximal neoplasia (8 %) compared to whites (2 %) (p value = 0.06) but a lower prevalence of any serrated-like (blacks 18 %, whites 32 %; p value = 0.02) and sessile serrated adenomas/polyps (blacks 2 %, whites 8 % Chi-square p value; p = 0.05).

conclusionsWithin this uninsured population, the overall prevalence of adenomas was high and nearly equal by race, but the racial differences observed between serrated and conventional polyp types emphasize the importance of taking polyp type into account in future research on this topic.

Indexed as

Black or African AmericanWhite PeopleAdenomatous PolypsColonic NeoplasmsColonic PolypsColonoscopyFemaleHealthcare DisparitiesHealth Status DisparitiesHumansMaleMedically UninsuredMiddle AgedPovertyPredictive Value of TestsPrevalenceColorectal adenomasRaceScreeningSerrated polypsSocioeconomic status

Identifiers

PMID26386856
PMCPMC5125220
OpenAlexW1944162113

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.