Evidence map›Paper›PMID 26386808›Full record

ArticleAmerican heart journal2015

Temporal trends in infective endocarditis epidemiology from 2007 to 2013 in Olmsted County, MN.

Daniel C DeSimone, Imad M Tleyjeh, Daniel D Correa de Sa, Nandan S Anavekar, Brian D Lahr, Muhammad R Sohail, James M Steckelberg, Walter R Wilson, Larry M Baddour

Open access · greenAbstract read
In one paragraph

Article in American heart journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 98 citations in OpenAlex.

  1. Infective endocarditis in a university hospital without on-site cardiac surgery: temporal trends over 37 years.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Infective Endocarditis: Still More Challenges Than Convictions.Arquivos brasileiros de cardiologia · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Surgery for infective endocarditis-analysis of factors affecting outcome.Indian journal of thoracic and cardiovascular surgery · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Daniel C DeSimoneDivision of Infectious Diseases, Mayo Clinic, Rochester, MN. Electronic address: desimone.daniel@mayo.edu.
Imad M TleyjehDivision of Infectious Diseases, Mayo Clinic, Rochester, MN; Division of Infectious Diseases, King Fahd Medical Center, Riyadh, Saudi Arabia.
Daniel D Correa de SaPrairie Cardiovascular Consultants, Carbondale, IL.
Nandan S AnavekarDivisions of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN.
Brian D LahrBiomedical Statistics and Informatics, Mayo Clinic College of Medicine, Rochester, MN.
Muhammad R SohailDivision of Infectious Diseases, Mayo Clinic, Rochester, MN; Divisions of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN.
James M SteckelbergDivision of Infectious Diseases, Mayo Clinic, Rochester, MN.
Walter R WilsonDivision of Infectious Diseases, Mayo Clinic, Rochester, MN.
Larry M BaddourDivision of Infectious Diseases, Mayo Clinic, Rochester, MN.
Mayo Clinic in Arizona · USMayo Clinic · USKing Fahd Medical City · SAPrairie Vascular Institute · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
ROCHESTER EPIDEMIOLOGY PROJECTR01AR030582 · NIAMS · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A · 1986 to 2009
$5.1M
NIAMS NIH HHS R01 AR030582NIA NIH HHS R01 AG034676NIA NIH HHS R01AG034676
6 · The paper itself

Abstract

backgroundThe aim of this study is to determine if there have been contemporary shifts in infective endocarditis (IE) epidemiology in our local population; an analysis of cases from 2007 to 2013 was conducted.

methodsThis is a population-based review of all adults (≥18 years) residing in Olmsted County, MN, with definite or possible IE using the Rochester Epidemiology Project from January 1, 2007, to December 31, 2013.

resultsWe identified 51 cases of IE in Olmsted County, MN, between 2007 and 2013. Median age of IE cases was 68.8 years (interquartile range 55.6-76.5), and 41% were females. Age- and sex-adjusted incidence of IE was 7.4 (95% CI 5.3-9.4) cases per 100,000 person-years. From a multivariable Poisson regression model, incidence of IE did not change significantly during the study period (P = .222) but was significantly higher in males and those of older age (P < .001). The annual incidences (per 100,000 person-years) were 2.5 for Staphylococcus aureus, 1.1 for viridans group streptococci, 1.6 for Enterococcus species, and 0.8 for coagulase-negative staphylococci. Only 19.6% (10/51) of Olmsted County patients underwent valve surgery between 2007 and 2013 as compared with 44.4% (197/444) of non-Olmsted County patients treated at Mayo Clinic Rochester.

conclusionIn this population-based study, no significant change in the overall incidence of IE in Olmsted County, MN, between 2007 and 2013 was seen, and it was similar to that seen between 1970 and 2006. Male gender and older age were associated with increased IE risk. With a lesser extent of cases attributable to viridans group streptococcal IE compared with previous years, S aureus was the predominant pathogen in IE cases during 2007 to 2013. The relatively low valve surgery rate was disparate from that reported from large, tertiary care centers (including our own) with non-population-based cohorts, which are subject to referral bias and can influence the expected characterization of IE.

Indexed as

Population SurveillanceAdolescentAdultAgedEndocarditisFemaleFollow-Up StudiesHumansMaleMiddle AgedMinnesotaMorbidityRetrospective StudiesRisk FactorsTime FactorsYoung Adult

Identifiers

PMID26386808
PMCPMC4677064
OpenAlexW2157531494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.