Evidence map›Paper›PMID 26386686›Full record

ReviewCurrent gastroenterology reports2015

Ulcerative Colitis: Update on Medical Management.

Heba N Iskandar, Tanvi Dhere, Francis A Farraye

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Interventions for the management of abdominal pain in ulcerative colitis.The Cochrane database of systematic reviews · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Heba N IskandarDepartment of Medicine, Division of Digestive Diseases, Emory University, 1365 Clifton Rd. NE, Building B, Suite 1200, Atlanta, GA, 30322, USA. heba.iskandar@emoryhealthcare.org.
Tanvi DhereDepartment of Medicine, Division of Digestive Diseases, Emory University, 1365 Clifton Rd. NE, Building B, Suite 1200, Atlanta, GA, 30322, USA.
Francis A FarrayeSection of Gastroenterology, Boston Medical Center, Boston University School of Medicine, 85 East Concord Street, Boston, MA, 02118, USA. francis.farraye@bmc.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic inflammatory bowel disease whose pathogenesis is multifactorial and includes influences from genes, the environment, and the gut microbiome. Recent advances in diagnosis and treatment have led to significant improvement in managing the disease. Disease monitoring with the use of therapeutic drug monitoring, stool markers, and assessment of mucosal healing have garnered much attention. The recent approval of vedolizumab for treatment of moderate to severe UC has been a welcome addition. Newer biologics, including those targeting the Janus tyrosine kinase (JAK) pathway, are on the horizon to add to the current armamentarium of anti-TNF alpha and anti-integrin therapies. The recent publication of the SCENIC consensus statement on surveillance and management of dysplasia in UC patients supports the use of chromoendoscopy over random biopsies in detecting dysplasia. This review highlights these recent advances along with others that have been made with ulcerative colitis.

Indexed as

Antibodies, Monoclonal, HumanizedBiological ProductsColitis, UlcerativeColorectal NeoplasmsDisease ManagementDrug MonitoringEarly Detection of CancerGastrointestinal AgentsHumansRisk FactorsSeverity of Illness IndexAntibodies, Monoclonal, HumanizedBiological ProductsGastrointestinal AgentsvedolizumabHealth maintenance in ulcerative colitisInflammatory bowel diseaseNew therapies in ulcerative colitisUlcerative colitisUlcerative colitis treatment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.