Evidence map›Paper›PMID 26386581›Full record

ArticleMycopathologia2016

Dermatophytosis due to Microsporum incurvatum: Notification and Identification of a Neglected Pathogenic Species.

Ali Rezaei-Matehkolaei, Koichi Makimura, Yvonne Graser, Seyedmojtaba Seyedmousavi, Mahdi Abastabar, Abdollah Rafiei, Ping Zhan, Ali Ronagh, Sima Jafarpour

Abstract readCase Reports
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In one paragraph

Article in Mycopathologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Ali Rezaei-MatehkolaeiDepartment of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran. a.r.matehkolaie@gmail.com.
Koichi MakimuraLaboratory of Space and Environmental Medicine, Graduate School of Medicine, Teikyo University, Tokyo, Japan.
Yvonne GraserConsiliary Laboratory for Dermatophytes, Institute of Microbiology, Charité-Universitätsmedizin Berlin, Dorotheenstrasse 96, Berlin, Germany.
Seyedmojtaba SeyedmousaviDepartment of Medical Microbiology, Radboud UMC, Nijmegen, The Netherlands.
Mahdi AbastabarDepartment of Medical Mycology and Parasitology, Invasive Fungi Research Center, School of Medicine, Mazandaran University of Medical Sciences, Sari, Islamic Republic of Iran.
Abdollah RafieiDepartment of Medical Laboratory Sciences, Paramedical Faculty, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran.
Ping ZhanDermatology Hospital of Jiangxi Province and Jiangxi Provincial Institute of Dermatology, Nanchang, 330001, Jiangxi, China.
Ali RonaghKhuzestan Administration of Environmental Protection, Ahvaz, Khuzestan, Islamic Republic of Iran.
Sima JafarpourDepartment of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran.
Ahvaz Jundishapur University of Medical Sciences · IRMazandaran University of Medical Sciences · IRCharité - Universitätsmedizin Berlin · DEIslamic Azad University, Ahvaz Branch · IRJiangxi Chest Hospital · CNTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 4-year-old Iranian boy developed erythematous, itchy and annular lesion on his face. Microscopic examination of the scraped samples with 10 % potassium hydroxide (KOH) revealed fungal septate hyphae and arthroconidia. The etiological agent was found to be Microsporum gypseum in mycological examinations. Amplification and restriction digestion of the internal transcribed spacers (ITS) of rDNA was not helpful for identification, but in ITS sequencing the isolate showed 98 % homology to Microsporum incurvatum strain CBS 172.64. Empirical treatment of the patient with griseofulvin for 4 weeks was successful. Other than our isolate, the ITS1 sequences of 38 strains from related species were retrieved from GenBank and phylogenetic tree using maximum likelihood method was constructed. The case isolate clustered apart from other strains of M. incurvatum. Pairwise comparison of ITS1 showed intraspecies variations of 0-13 nucleotides among M. incurvatum strains and an extensive interspecies variation of 33-80 bp and remarkable interspecies size polymorphism between the three sister species in the M. gypseum complex. The high level of ITS1 intraspecific variation is suitable for species identification rather than phylogeographic analysis of M. gypseum complex.

Indexed as

Antifungal AgentsChild, PreschoolCluster AnalysisDNA, FungalDNA, Ribosomal SpacerFaceGriseofulvinHumansIranMaleMicroscopyMicrosporumMolecular Sequence DataNeglected DiseasesPhylogenySequence Analysis, DNAAntifungal AgentsDNA, FungalDNA, Ribosomal SpacerGriseofulvinITSMicrosporum gypseumMicrosporum incurvatumPhylogeny

Identifiers

PMID26386581
OpenAlexW1711528582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.