Evidence map›Paper›PMID 26386473›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2016

Perceived Health Risks of Snus and Medicinal Nicotine Products.

Dorothy K Hatsukami, R I Vogel, Herb H Severson, Joni A Jensen, Richard J O'Connor

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
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  9. Smokeless Tobacco in Uganda: Perceptions among Tobacco Control Stakeholders.International journal of environmental research and public health · 2022
    Article
  10. Article
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  18. Low Nicotine Content Descriptors Reduce Perceived Health Risks and Positive Cigarette Ratings in Participants Using Very Low Nicotine Content Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Dorothy K HatsukamiDepartment of Psychiatry, Tobacco Research Programs, University of Minnesota, Minneapolis, MN; hatsu001@umn.edu.
R I VogelBiostatistics and Bioinformatics Core, Masonic Cancer Center, University of Minnesota, Minneapolis, MN;
Herb H SeversonDepartment of Psychology, Oregon Research Institute, Eugene, OR;
Joni A JensenDepartment of Psychiatry, Tobacco Research Programs, University of Minnesota, Minneapolis, MN;
Richard J O'ConnorDepartment of Health Behavior, Roswell Park Cancer Institute, Buffalo, NY.
University of Minnesota · USOregon Research Institute · USRoswell Park Comprehensive Cancer Center · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Jeffrey S. Miller · 1998 to 2026
$100.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Tobacco Constituent and Biomarker Assessment CoreU19CA157345 · NCI · UNIVERSITY OF MINNESOTA · PI HATSUKAMI, DOROTHY K · 2012 to 2016
$13.3M
Evaluation of Oral Tobacco as a Harm Reduction Method for SmokersR01CA135884 · NCI · UNIVERSITY OF MINNESOTA · PI HATSUKAMI, DOROTHY K · 2008 to 2013
$2.7M
NCATS NIH HHS UL1 TR000114NCATS NIH HHS UL1TR000114NCATS NIH HHS UL1 TR002494NCI NIH HHS P30 CA077598NCI NIH HHS R01 CA135884NCI NIH HHS R01CA135884NCI NIH HHS U19 CA157345NCI NIH HHS U19CA157345
6 · The paper itself

Abstract

introductionPerceived health risk (PHR) of a tobacco product may influence both uptake and continued use. In this study, we examined PHRs of snus and medicinal nicotine using the PHR scale and the relationship of PHR responses to use of these products in smokers seeking an alternative to smoking.

methodsSmokers were randomly assigned to snus or to medicinal nicotine for a period of 12 weeks and asked to only use the assigned product. The PHR scale involves rating the extent of perceived risk of a product for different diseases and was given at baseline and weeks 4 and 12 during treatment. Relationships between PHR scale scores and study attrition, compliance with only using the product, and continued use of the product after treatment were determined.

resultsResponse to the PHR scale showed no significant differences between the snus and medicinal nicotine for perceived risks for lung cancer, emphysema, and bronchitis. However, significant differences were observed for other cancers, heart disease, stroke and risk for addiction, particularly after product use, with higher scores among those assigned to snus. Scores on the PHR scale were not related to any of the trial outcome variables.

conclusionsAmong smokers seeking an alternative to smoking in a clinic setting, PHR of a product changes after product use but may not be related to product use patterns. IMPLICATIONS: PHRs of snus or medicinal nicotine in smokers assigned to these products become more accurate after product use. PHR does not appear to be associated with patterns of product use; rather satisfaction with a product is a better indicator as to whether a smoker is compliant with only using the product or continues to use the product.

Indexed as

Smoking PreventionTobacco Use Cessation DevicesAgedBehavior, AddictiveBronchitisEmphysemaFemaleHarm ReductionHumansLung NeoplasmsMaleMiddle AgedNicotinePatient CompliancePatient DropoutsPatient SatisfactionNicotine

Identifiers

PMID26386473
PMCPMC5896824
OpenAlexW2333397706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.