Evidence map›Paper›PMID 26385943›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias2016

Uric Acid and the Risk of Alzheimer's Disease: Is There an Association?

Min Yuan, Lijun Xu, Xiaoping Yin

Open access · bronzeAbstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Min YuanDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Lijun XuDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Xiaoping YinDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China xiaopingbuxiao@126.com xulijun20050901@sina.com.
Nanchang University · CNSecond Affiliated Hospital of Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a very common neurodegenerative disorder of the central nervous system, characterized by dementia, cognitive impairment, and memory loss, and the global prevalence is increasing. Many epidemiologic studies have considered the association between uric acid and AD, yet the relationship remains elusive. The objective of this study was to validate whether or not uric acid is indeed associated with AD. We compared different prospective studies and ultimately found that it is also a controversial issue. Further higher quality prospective evidence on the relationship between uric acid and AD in different age stage are needed to determine the causal association and its exact pathogenetic mechanisms.

Indexed as

AgedAged, 80 and overAlzheimer DiseaseFemaleHumansMaleMiddle AgedRiskUric AcidUric AcidAlzheimer’s diseaseneurodegenerative disorderoxidative stressuric acid

Identifiers

PMID26385943
PMCPMC10852652
OpenAlexW2337003927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.