ArticlePediatric nephrology (Berlin, Germany)2016
Anemia in children following renal transplantation-results from the ESPN/ERA-EDTA Registry.
Article in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04292418 (Predictors of Rejection in Pediatric Kidney Transplantation), which is not on this map. Cited by 13 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Predictors of Rejection in Pediatric Kidney Transplantation
Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- [Incidence and associated factors of anemia within six months after kidney transplantation in pediatric recipients].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- Trends in the epidemiology of paediatric kidney transplantation in Europe between 2010 and 2021: an ESPN/ERA Registry study.Clinical kidney journal · 2026Article
- Anemia after kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2023Article
- Risk factors and current state of therapy for anemia after kidney transplantation.Frontiers in medicine · 2023Review
- Anemia in Pediatric Kidney Transplant Recipients-Etiologies and Management.Frontiers in pediatrics · 2022Review
- Associations among erythropoietic, iron-related, and FGF23 parameters in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2021Article
- The potential impact of hematocrit correction on evaluation of tacrolimus target exposure in pediatric kidney transplant patients.Pediatric nephrology (Berlin, Germany) · 2019Article
- Prevalence and predictors of blood transfusion after pediatric kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2018Article
- Adverse Events under Tacrolimus and Cyclosporine in the First 3 Years Post-Renal Transplantation in Children.Clinical drug investigation · 2018Article
- Cardiovascular risks in chronic kidney disease pediatric patients.Experimental and therapeutic medicine · 2017Article
- Tacrolimus dose requirements in paediatric renal allograft recipients are characterized by a biphasic course determined by age and bone maturation.British journal of clinical pharmacology · 2017Article
- Anemia and low-grade inflammation in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2017Article
- Lessons learned from the ESPN/ERA-EDTA Registry.Pediatric nephrology (Berlin, Germany) · 2016Review
Corrections and comments
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Authors and funding
15 authors at 10 institutions in 12 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur aim was to determine the prevalence of sub-target hemoglobin (Hb) levels in children with a renal allograft and to identify potential determinants associated with these Hb levels.
methodsData from 3669 children with a functioning renal allograft, aged <18 years between 1 January 2000 and 31 December 2012, from 20 European countries were retrieved from the ESPN/ERA-EDTA Registry, providing 16,170 Hb measurements.
resultsAccording to the NKF/KDOQI classification and the UK-NICE guidelines, 49.8 and 7.8% of the patients, respectively, were anemic. Hb levels were strongly associated with graft function, with Hb levels of 12.6 g/dl in children with chronic kidney disease (CKD) stage 1, declining to 10.7 g/dl in children with CKD stage 5 (P < 0.001). Higher Hb levels were associated with the use of tacrolimus compared to ciclosporin (0.14 g/dl; 95% confidence interval 0.02-0.27; P = 0.002). Low Hb levels were associated with an increased risk of graft failure (P = 0.01) or combined graft failure and death (P < 0.01), but not with death alone (not significant).
conclusionsAnemia is present in a significant proportion of European pediatric kidney transplant recipients and is associated with renal allograft dysfunction and type of immunosuppressants used. In our patient cohort, higher Hb levels were associated with better graft and patient survival and less hypertension.
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