Evidence map›Paper›PMID 26384950›Full record

ArticleInternational journal of STD & AIDS2016

Acceptability and preferences for safer conception HIV prevention strategies: a qualitative study.

Sheree R Schwartz, Nora West, Rebecca Phofa, Nompumelelo Yende, Ian Sanne, Jean Bassett, Annelies Van Rie

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. "Sexual and reproductive health matters · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sheree R SchwartzDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD, USA sschwartz@jhu.edu.
Nora WestWitkoppen Health and Welfare Centre, Johannesburg, South Africa.
Rebecca PhofaWitkoppen Health and Welfare Centre, Johannesburg, South Africa.
Nompumelelo YendeWitkoppen Health and Welfare Centre, Johannesburg, South Africa.
Ian SanneClinical HIV Research Unit, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa Right to Care, Johannesburg, South Africa.
Jean BassettWitkoppen Health and Welfare Centre, Johannesburg, South Africa.
Annelies Van RieDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
FIC NIH HHS R25 TW009340
6 · The paper itself

Abstract

Safer conception strategies to reduce the HIV transmission risk include antiretroviral therapy for HIV-positive partners, pre-exposure prophylaxis for HIV-negative partners, condomless sex limited to fertile periods, and home-based self-insemination. Resistance to taking treatment or cultural concerns may limit uptake of strategies and intervention success. Understanding the acceptability and preferences between different approaches is important to optimise service delivery. Between February and July 2013, 42 adults (21 HIV-positive and 21 HIV-negative) receiving primary care at Witkoppen Health and Welfare Centre in Johannesburg, South Africa, participated in focus group discussions or in-depth interviews. Themes were analysed using a grounded theory approach. Acceptability of antiretroviral-based strategies varied. Concerns over side effects, antiretroviral treatment duration and beliefs that treatment is only for the sick were common barriers; however, desperation for a child was noted as a facilitator for uptake. HIV-negative men and HIV-positive women had favourable attitudes towards self-insemination, though paternity and safety concerns were raised. Self-insemination was generally preferred over pre-exposure prophylaxis by HIV-negative men, and antiretroviral-based strategies were preferred by couples with HIV-negative female partners, despite concerns raised about condomless sex while virally suppressed. Knowledge about the fertile window was low. A strong counselling component will be required for effective uptake and adherence to safer conception services.

Indexed as

Family CharacteristicsFertilizationPatient Acceptance of Health CarePatient PreferencePre-Exposure ProphylaxisAdultCounselingFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansInfectious Disease Transmission, VerticalInterviews as TopicMaleMiddle Ageddiscordant couplesfertility intentionsHIV-1HIV preventionsafer conception

Identifiers

PMID26384950
PMCPMC4889551

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.