ArticleJournal of neurology, neurosurgery, and psychiatry2016
Meyer's loop asymmetry and language lateralisation in epilepsy.
Article in Journal of neurology, neurosurgery, and psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Does white matter structure relate to hemispheric language lateralization? A systematic review.Brain communications · 2026Review
- Diffusion magnetic resonance imaging connectome features are predictive of functional lateralization of semantic processing in the anterior temporal lobes.Human brain mapping · 2023Article
- Volumetric analysis of the piriform cortex in temporal lobe epilepsy.Epilepsy research · 2022Article
- Tracing in vivo the dorsal loop of the optic radiation: convergent perspectives from tractography and electrophysiology compared to a neuroanatomical ground truth.Brain structure & function · 2022Article
- XTRACT - Standardised protocols for automated tractography in the human and macaque brain.NeuroImage · 2020Article
- Microstructural Investigations of the Visual Pathways in Pediatric Epilepsy Neurosurgery: Insights From Multi-Shell Diffusion Magnetic Resonance Imaging.Frontiers in neuroscience · 2020Article
- The Effect of Vascular Segmentation Methods on Stereotactic Trajectory Planning for Drug-Resistant Focal Epilepsy: A Retrospective Cohort Study.World neurosurgery: X · 2019Article
- Optic Radiation Tractography in Pediatric Brain Surgery Applications: A Reliability and Agreement Assessment of the Tractography Method.Frontiers in neuroscience · 2019Article
- Getting the best outcomes from epilepsy surgery.Annals of neurology · 2018Review
- Meyer's loop tractography for image-guided surgery depends on imaging protocol and hardware.NeuroImage. Clinical · 2018Article
- Active delineation of Meyer's loop using oriented priors through MAGNEtic tractography (MAGNET).Human brain mapping · 2017Article
- White matter tractography for neurosurgical planning: A topography-based review of the current state of the art.NeuroImage. Clinical · 2017Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectivesSeveral studies have suggested an asymmetry in Meyer's loop in individuals, with the left loop anterior to the right. In this study we test the hypothesis that there is an association between Meyer's loop asymmetry (MLA) and language lateralisation.
methods57 patients with epilepsy were identified with language functional MRI (fMRI) and diffusion MRI acquisition. Language lateralisation indices from fMRI(LI) and optic radiation and arcuate fasciculus probabilistic tractography was performed for each subject. The subjects were divided into left language dominant (LI>0.4) and non-left language groups (LI<0.4) according to their LI.
resultsA negative linear correlation was identified between language lateralisation and MLA, with greater left lateralised language associated with more anteriorly placed left Meyer's loops (R value -0.34, p=0.01). There was a significant difference in mean MLA between the two groups, with the left loop being anterior to the right loop in the LI>0.4 group and posterior to the right loop in the LI<0.4 group (p=0.003). No correlation was found between language lateralisation and arcuate fasciculus volume.
conclusionsThis study suggests an association between the extent of Meyer's loop asymmetry and the lateralisation of language determined by fMRI in patients with epilepsy. Further studies should be carried out to evaluate this association in control subjects and with other measures of language lateralisation.
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