ArticleJournal of cardiothoracic surgery2015
Right versus left transthoracic approach for lymph node-negative esophageal squamous cell carcinoma.
Article in Journal of cardiothoracic surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Comparison of right- and left-approach esophagectomy for esophageal cancer: a meta-analysis.Frontiers in oncology · 2025Review
- Left compared with right thoracic approach thoracotomy in esophageal cancer: a retrospective cohort study.Journal of cancer research and clinical oncology · 2023Article
- Efficacy and safety of esophagectomy via left thoracic approach versus via right thoracic approach for middle and lower thoracic esophageal cancer: a multicenter randomized clinical trial (NST1501).Annals of translational medicine · 2022Article
- Left versus right approach for middle and lower esophageal squamous cell carcinoma: A propensity score-matched study.Frontiers in oncology · 2022Article
- Survival risk prediction model for patients with pTJournal of cardiothoracic surgery · 2021Article
- TRANSHIATAL ESOPHAGECTOMY IN SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS: WHAT ARE THE BEST INDICATIONS?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021Article
- Risk factors for tumor recurrence in patients with pTThe Journal of international medical research · 2020Article
- Comparison of Ivor Lewis esophagectomy and Sweet esophagectomy for the treatment of middle-lower esophageal squamous cell carcinoma.Journal of thoracic disease · 2019Article
- Transhiatal versus Left Transthoracic Esophagectomy for Gastroesophageal Junction Cancer; The Impact of Surgical Approach on Postoperative Complications.Middle East journal of digestive diseases · 2019Article
- Long-term survival of the middle and lower thoracic esophageal cancer patients after surgical treatment through left or right thoracic approach.Journal of thoracic disease · 2018Article
- Efficacy comparison of transcervical video-assisted mediastinoscopic lymphadenectomy combined with left transthoracic esophagectomy versus right transthoracic esophagectomy for esophageal cancer treatment.World journal of surgical oncology · 2018Article
- Comparison of short-term outcomes and three yearsurvival between total minimally invasive McKeown and dual-incision esophagectomy.Thoracic cancer · 2017Article
- The impact of operative approaches on outcomes of middle and lower third esophageal squamous cell carcinoma.Journal of thoracic disease · 2016Article
- Left thoracotomy for middle or lower thoracic esophageal carcinoma: still Sweet enough?Journal of thoracic disease · 2016Article
- Epidermal growth factor receptor and B7-H3 expression in esophageal squamous tissues correlate to patient prognosis.OncoTargets and therapy · 2016Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo compare the right and left transthoracic approach on the post-operative survival of patients with lymph node-negative esophageal squamous cell carcinoma.
methodsSix hundred and ninety-five ESCC patients who underwent esophagectomy between 1990 and 2005 were retrospectively enrolled in the present study and were confirmed by histology to be of no lymph node metastasis. Those who had received neoadjuvant chemotherapy or radiotherapy were excluded from the study. Patients were divided into two groups, the left (n=545) and right (n=150) transthoracic groups. The follow-up duration ranged from 1 to 20 years with a mean of 7 years. Kaplan-Meier and univariate and multivariate Cox proportional hazards were used for analysis.
results3- and 5-year CSS rates were 62.0 % and 44.0 % in the left group, while the corresponding figures in the right group were 56.0 % and 40.0 %(P<0.05). The overall survival for the two groups was significantly different (P=0.045). Survival analyses were stratified by stages, which found that the favorable survival advantage was not present. When the survival curves were stratified by tumor locations, a significant difference was not revealed. Surgical approaches were regarded as one of the prognostic factors in the univariate analysis (P=0.019). However, this significance could not be confirmed in multivariate Cox regression analysis (P=0.193).
conclusionsThe left transthoracic approach is superior in some aspects to the right transthoracic approach regarding surgical and oncological outcomes in the treatment of lymph node negative ESCC.
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