Evidence map›Paper›PMID 26384373›Full record

ArticleDatabase : the journal of biological databases and curation2015

FARE-CAFE: a database of functional and regulatory elements of cancer-associated fusion events.

Praveen Kumar Korla, Jack Cheng, Chien-Hung Huang, Jeffrey J P Tsai, Yu-Hsuan Liu, Nilubon Kurubanjerdjit, Wen-Tsong Hsieh, Huey-Yi Chen, Ka-Lok Ng

Open access · goldAbstract readDataset
PubMed Full text at PMC Publisher
In one paragraph

Article in Database : the journal of biological databases and curation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Molecular Signatures of Fusion Proteins in Cancer.ACS pharmacology & translational science · 2019
    Article
  7. Identification of a Recurrent LMO7-BRAF Fusion in Papillary Thyroid Carcinoma.Thyroid : official journal of the American Thyroid Association · 2018
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Praveen Kumar KorlaDepartment of Bioinformatics and Medical Engineering, Asia University, Taichung 41354, Taiwan.
Jack ChengGraduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Chien-Hung HuangDepartment of Computer Science and Information Engineering, National Formosa University, Yunlin 632, Taiwan.
Jeffrey J P TsaiDepartment of Bioinformatics and Medical Engineering, Asia University, Taichung 41354, Taiwan.
Yu-Hsuan LiuDepartment of Computer Science and Information Engineering, National Formosa University, Yunlin 632, Taiwan.
Nilubon KurubanjerdjitSchool of Information Technology, Mae Fah Luang University, Chiang Rai 57100, Thailand.
Wen-Tsong HsiehDepartment of Pharmacology, China Medical University, Taichung 40402, Taiwan.
Huey-Yi ChenDepartment of Obstetrics and Gynecology, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan, and.
Ka-Lok NgDepartment of Bioinformatics and Medical Engineering, Asia University, Taichung 41354, Taiwan, Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan ppiddi@gmail.com.
Asia University · TWChina Medical University · TWNational Formosa University · TWMae Fah Luang University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosomal translocation (CT) is of enormous clinical interest because this disorder is associated with various major solid tumors and leukemia. A tumor-specific fusion gene event may occur when a translocation joins two separate genes. Currently, various CT databases provide information about fusion genes and their genomic elements. However, no database of the roles of fusion genes, in terms of essential functional and regulatory elements in oncogenesis, is available. FARE-CAFE is a unique combination of CTs, fusion proteins, protein domains, domain-domain interactions, protein-protein interactions, transcription factors and microRNAs, with subsequent experimental information, which cannot be found in any other CT database. Genomic DNA information including, for example, manually collected exact locations of the first and second break points, sequences and karyotypes of fusion genes are included. FARE-CAFE will substantially facilitate the cancer biologist's mission of elucidating the pathogenesis of various types of cancer. This database will ultimately help to develop 'novel' therapeutic approaches. Database URL: http://ppi.bioinfo.asia.edu.tw/FARE-CAFE.

Indexed as

Databases, GeneticDNA, NeoplasmNeoplasm ProteinsNeoplasmsResponse ElementsAnimalsHumansDNA, NeoplasmNeoplasm Proteins

Identifiers

PMID26384373
PMCPMC4684693
OpenAlexW2197382876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.