Evidence map›Paper›PMID 26383882›Full record

Trial reportPediatric research2016

Preventative effect of ondansetron on postanesthesia shivering in children undergoing caudal anesthesia: a randomized double-blinded clinical trial.

Hongfei Lin, Jiangmei Wang, Ziying Jin, Yaoqin Hu, Wenfang Huang

Open access · bronzeAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Pediatric research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hongfei LinDepartment of Anesthesiology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jiangmei WangDepartment of Anesthesiology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Ziying JinDepartment of Anesthesiology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Yaoqin HuDepartment of Anesthesiology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Wenfang HuangDepartment of Anesthesiology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Children's Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOndansetron has been shown to decrease postanesthesia shivering in adults, but this effect has never been studied in children. This study aimed to determine whether ondansetron decreases postanesthesia shivering in children undergoing caudal anesthesia.

methodsFifty-nine 8- to 13-y-old children undergoing both intravenous and caudal anesthesia were included. As soon as anesthetization and caudal block were complete, children were given intravenous injections of 4 mg ondansetron or an equal volume of normal saline. Heart rate, blood pressure, oxygen saturation (SpO2), and body temperature were recorded just before application of general anesthesia to children and immediately upon entry into the recovery room after awakening from anesthesia. The shivering score was assessed, using a 4-point scale of severity, immediately upon entry into the recovery room after awakening from anesthesia, 15 min after entry into the recovery room, and 30 min after entry into the recovery room.

resultsTreatment with ondansetron was associated with decreased odds of postanesthesia shivering symptoms compared to the control group. There was also a significant decrease in shivering score with time after anesthesia.

conclusionOndansetron decreases postanesthesia shivering in children receiving caudal block after intravenous anesthesia.

Indexed as

Anesthesia, CaudalAdolescentAnestheticsBlood PressureBody TemperatureChildDouble-Blind MethodFemaleHeart RateHumansInjections, IntravenousMaleOndansetronOxygenPostoperative ComplicationsProspective StudiesAnestheticsOndansetronOxygen

Identifiers

PMID26383882
OpenAlexW2405584594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.