Evidence map›Paper›PMID 26383173›Full record

ArticleClinical transplantation2015

Comparing 10-yr renal outcomes in deceased donor and living donor liver transplants.

Shaifali Sandal, Anthony Almudevar, Sandesh Parajuli, Anirban Bose

Open access · greenAbstract readComparative Study
In one paragraph

Article in Clinical transplantation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Shaifali SandalDivision of Nephrology, University of Rochester Medical Center, Rochester, NY, USA.
Anthony AlmudevarDepartment of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, USA.
Sandesh ParajuliDivision of Nephrology, University of Rochester Medical Center, Rochester, NY, USA.
Anirban BoseDivision of Nephrology, University of Rochester Medical Center, Rochester, NY, USA.
University of Rochester Medical Center · USMcGill University Health Centre · CA

Funding

The University of Rochester's Clinical and Translational Science InstituteUL1TR000042 · NCATS · UNIVERSITY OF ROCHESTER · PI BENNETT, NANCY M, KIEBURTZ, KARL D. · 2012 to 2015
$14.4M
NCATS NIH HHS UL1 TR000042NCATS NIH HHS UL1TR000042
6 · The paper itself

Abstract

Few studies have explored whether the type of LT, deceased donor LT (DDLT) or living donor LT (LDLT), impacts long-term renal outcomes. We performed a retrospective analysis of 220 LT recipients at our institution to study their renal outcomes at 10 yr. Exclusion criteria were age ≤ 18 yr, graft survival ≤ 6 months, and multiorgan transplants; 108 DDLTs and 62 LDLTs were eligible. At baseline, DDLTs had a lower eGFR than LDLTs and 10.2% of DDLTs were on dialysis as compared to 0% of LDLTs. At 10 yr, seven DDLT and three LDLT recipients required dialysis or renal transplant (p = 0.75). In recipients with graft survival >6 months, DDLTs had a slower decline in eGFR as compared to LDLTs (p < 0.01). Among LDLTs, the decline in eGFR continued over the entire 10-yr period, whereas among DDLTs, the decline in eGFR slowed significantly after six months (p = 0.01). This difference between the two groups was not seen among patients in the highest quartile of baseline eGFR. Patient survival and graft survival were similar. In conclusion, the incidence of end-stage renal disease was similar in both DDLT and LDLT patients, but LDLT recipients seem to have a more sustained decline in eGFR when compared with DDLT recipients.

Indexed as

Living DonorsPostoperative ComplicationsCadaverFemaleFollow-Up StudiesGlomerular Filtration RateGraft RejectionGraft SurvivalHumansIncidenceKidney Function TestsLiver TransplantationMaleMiddle AgedPrognosisProspective Studiesdeceased donorliver transplantliving donorrenal outcomes

Identifiers

PMID26383173
PMCPMC4715595
OpenAlexW1935690703

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.