ArticleNature communications2015
The Lingula genome provides insights into brachiopod evolution and the origin of phosphate biomineralization.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.
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Who cites it
92 citing papers in PubMed, 202 citations in OpenAlex.
- The preservation of francolite-associated sulfate in lingulid brachiopods.Chemical geology · 2026Article
- Proteomic Analysis of Biomineralization Proteins in the Shell Plates and Spicules of ChitonAnimals : an open access journal from MDPI · 2026Article
- Comparative Proteomics Reveals Conserved and Lineage-Specific Molecular Toolkits in Lophotrochozoan Biomineralization.Genome biology and evolution · 2026Article
- ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026Article
- Brachiopod genome unveils the evolution of BMP signalling in bilaterian body patterning.Nature communications · 2026Article
- Evolutionary innovation within conserved gene regulatory networks underlying biomineralized skeletons in Bilateria.Molecular biology and evolution · 2026Article
- Chromosome-level haplotype-resolved genome assembly of the linguliform brachiopod Discradisca antillarum (d'Orbigny, 1845).G3 (Bethesda, Md.) · 2025Article
- Article
- Widespread presence of bone marrow-like hematopoietic stem cell niche in invertebrate skeletons.Science advances · 2025Article
- Molluscan Shells, Spicules, and Gladii Are Evolutionarily Deeply Conserved.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025Article
- Phosphatic stromatoporoid sponges formed reefs ~480 Mya.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Exceptionally Preserved Setae: A Possible Morphological Synapomorphy of Cambrian Lophotrochozoans.Evolution & development · 2025Article
- Exploring proteins within the coccolith matrix.Scientific reports · 2024Article
- Combinatorial Wnt signaling landscape during brachiopod anteroposterior patterning.BMC biology · 2024Article
- Diversification of von Willebrand Factor A and Chitin-Binding Domains in Pif/BMSPs Among Mollusks.Journal of molecular evolution · 2024Article
- Transcriptional profiling of Bulinus globosus provides insights into immune gene families in snails supporting the transmission of urogenital schistosomiasis.Developmental and comparative immunology · 2024Review
- Article
- MarFERReT, an open-source, version-controlled reference library of marine microbial eukaryote functional genes.Scientific data · 2023Article
- Genomic and transcriptomic survey of bryozoan Hox and ParaHox genes with emphasis on phylactolaemate bryozoans.BMC genomics · 2023Article
- Single-cell transcriptomics refuels the exploration of spiralian biology.Briefings in functional genomics · 2023Review
32 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evolutionary origins of lingulid brachiopods and their calcium phosphate shells have been obscure. Here we decode the 425-Mb genome of Lingula anatina to gain insights into brachiopod evolution. Comprehensive phylogenomic analyses place Lingula close to molluscs, but distant from annelids. The Lingula gene number has increased to ∼34,000 by extensive expansion of gene families. Although Lingula and vertebrates have superficially similar hard tissue components, our genomic, transcriptomic and proteomic analyses show that Lingula lacks genes involved in bone formation, indicating an independent origin of their phosphate biominerals. Several genes involved in Lingula shell formation are shared by molluscs. However, Lingula has independently undergone domain combinations to produce shell matrix collagens with EGF domains and carries lineage-specific shell matrix proteins. Gene family expansion, domain shuffling and co-option of genes appear to be the genomic background of Lingula's unique biomineralization. This Lingula genome provides resources for further studies of lophotrochozoan evolution.
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