Evidence map›Paper›PMID 26382068›Full record

ArticlePloS one2015

Low to Moderate Average Alcohol Consumption and Binge Drinking in Early Pregnancy: Effects on Choice Reaction Time and Information Processing Time in Five-Year-Old Children.

Tina R Kilburn, Hanne-Lise Falgreen Eriksen, Mette Underbjerg, Poul Thorsen, Erik Lykke Mortensen, Nils Inge Landrø, Leiv S Bakketeig, Jakob Grove, Claus Sværke, Ulrik Schiøler Kesmodel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Reducing the Prevalence of Alcohol-Exposed Pregnancies in the United States: A Simulation Modeling Study.Medical decision making : an international journal of the Society for Medical Decision Making · 2022
    Article
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Tina R KilburnDepartment of Research, Child and Adolescent Psychiatry, Aarhus University Hospital, Risskov, Denmark.
Hanne-Lise Falgreen EriksenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Mette UnderbjergVejlefjord Rehabilitation Center, Stouby, Denmark.
Poul ThorsenDepartment of Obstetrics and Gynaecology, Lillebælt Hospital, Kolding, Denmark.
Erik Lykke MortensenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark; Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark.
Nils Inge LandrøClinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway.
Leiv S BakketeigNational Institute of Public Health, University of Oslo, Oslo, Norway.
Jakob GroveDepartment of Biomedicine, Aarhus University, Aarhus, Denmark; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
Claus SværkeClinical Epidemiology, Aarhus University, Aarhus, Denmark.
Ulrik Schiøler KesmodelDepartment of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Aarhus University · DKUniversity of Copenhagen · DKUniversity of Oslo · NOAarhus University Hospital · DKLillebaelt Hospital · DKVejle Sygehus · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeficits in information processing may be a core deficit after fetal alcohol exposure. This study was designed to investigate the possible effects of weekly low to moderate maternal alcohol consumption and binge drinking episodes in early pregnancy on choice reaction time (CRT) and information processing time (IPT) in young children.

methodParticipants were sampled based on maternal alcohol consumption during pregnancy. At the age of 60-64 months, 1,333 children were administered a modified version of the Sternberg paradigm to assess CRT and IPT. In addition, a test of general intelligence (WPPSI-R) was administered.

resultsAdjusted for a wide range of potential confounders, this study showed no significant effects of average weekly maternal alcohol consumption during pregnancy on CRT or IPT. There was, however, an indication of slower CRT associated with binge drinking episodes in gestational weeks 1-4.

conclusionThis study observed no significant effects of average weekly maternal alcohol consumption during pregnancy on CRT or IPT as assessed by the Sternberg paradigm. However, there were some indications of CRT being associated with binge drinking during very early pregnancy. Further large-scale studies are needed to investigate effects of different patterns of maternal alcohol consumption on basic cognitive processes in offspring.

Indexed as

AdultAlcohol DrinkingBinge DrinkingChild, PreschoolChoice BehaviorFemaleHumansMaleNeuropsychological TestsPregnancyPrenatal Exposure Delayed EffectsReaction Time

Identifiers

PMID26382068
PMCPMC4575046
OpenAlexW2191998379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.