Evidence map›Paper›PMID 26381681›Full record

ArticleThe American journal of emergency medicine2015

Treatment of bacterial skin infections in ED observation units: factors influencing prescribing practice.

John P Haran, Gregory Wu, Vanni Bucci, Andrew Fischer, Edward W Boyer, Patricia L Hibberd

Abstract read
In one paragraph

Article in The American journal of emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Contemporary clinical trials communications · 2023
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John P HaranDepartment of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA. Electronic address: john.haran@umassmed.edu.
Gregory WuDepartment of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA.
Vanni BucciDepartment of Biology, University of Massachusetts Dartmouth, North Dartmouth, MA.
Andrew FischerDepartment of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA.
Edward W BoyerDepartment of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA.
Patricia L HibberdDepartment of Pediatrics and Division of Global Health, Massachusetts General Hospital, Boston, MA.

Funding

Midcareer Investigator Award in Patient-Oriented Research (K24)K24AT003683 · NCCIH · TUFTS MEDICAL CENTER · PI HIBBERD, PATRICIA L · 2006 to 2015
$1.9M
Mentoring in Advanced mHealth Technologies and Machine Learning for HIV/Drug Abuse ResearchK24DA037109 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BOYER, EDWARD W · 2014 to 2025
$1.9M
Mathematical modeling from metagenomics - minimizing risk of enteric infectionsR15AI112985 · NIAID · UNIVERSITY OF MASSACHUSETTS DARTMOUTH · PI BUCCI, VANNI · 2015 to 2015
$465k
NCCIH NIH HHS 5K24AT003683-09NCCIH NIH HHS K24 AT003683NIAID NIH HHS 1R15AI112985-01A1NIAID NIH HHS L30 AI107834NIAID NIH HHS R15 AI112985NIDA NIH HHS K24 DA037109
6 · The paper itself

Abstract

objectiveThe Infectious Disease Society of America (IDSA) publishes evidence-based guidelines for the treatment of skin and soft tissue infections. How closely physicians follow these guidelines is unknown, particularly in the emergency department observation unit (EDOU) where increasing numbers of patients are treatment for these infections. Our objectives were to describe (1) the antibiotic treatment patterns EDOU patients, (2) physicians' adherence to the IDSA guidelines, and (3) factors that influence physician's prescribing practices.

methodsThis prospective cohort enrolled adult patients discharged from an EDOU at an academic medical center after treatment for a skin or soft tissue infection. Information was collected from chart review and patient interview pertaining to the patient's sociodemographic characteristics, presenting illness, and antibiotic treatment regimens. Treatment regimens were compared with national guidelines.

resultsThe study included 193 patients of which only 43% were treated according to IDSA guidelines, 42% were overtreated, and 15% were undertreated. Women were more likely to be undertreated (relative risk, 1.58; 95% confidence interval, 1.21-2.06), whereas patients 50 years and older were at risk for overtreatment (relative risk, 1.44; 95% confidence interval, 1.03-2.02). Women also received shorter courses of antibiotic therapy with an average of 9.6 days of treatment compared with 10.6 days for men.

conclusionsPhysician antibiotic prescribing practices demonstrated poor adherence to IDSA guidelines and were influenced by the patient's age and sex. Standardized antibiotic protocols for treatment of skin and soft tissue infections to IDSA guidelines in the EDOU would minimize physician bias.

Indexed as

Emergency Service, HospitalPractice Patterns, Physicians'AdultAgedAge FactorsAnti-Bacterial AgentsCohort StudiesFemaleGuideline AdherenceHumansMaleMiddle AgedPractice Guidelines as TopicSex FactorsSkin Diseases, BacterialSoft Tissue InfectionsAnti-Bacterial Agents

Identifiers

PMID26381681
PMCPMC4679601

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.