ArticleNature communications2015
Ultrafast multidimensional Laplace NMR for a rapid and sensitive chemical analysis.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Quantification of Ligand-Membrane Interactions Using DNP-NMR Relaxometry.Analytical chemistry · 2026Article
- NMR Relaxometry Across Time: From Early Insights to Emerging Directions.Magnetic resonance in chemistry : MRC · 2025Article
- High-confidence reconstruction for Laplace inversion in NMR based on uncertainty-informed deep learning.Science advances · 2025Article
- UltrafastAnalytical chemistry · 2024Article
- Ultrafast Nuclear Magnetic Resonance as a Tool to Detect Rapid Chemical Change in Solution.ACS physical chemistry Au · 2024Review
- Measuring Protein-Ligand Binding by Hyperpolarized Ultrafast NMR.Journal of the American Chemical Society · 2024Article
- SHARPER-DOSY: Sensitivity enhanced diffusion-ordered NMR spectroscopy.Nature communications · 2023Article
- SPICY: a method for single scan rotating frame relaxometry.Physical chemistry chemical physics : PCCP · 2023Article
- Data inversion of multi-dimensional magnetic resonance in porous media.Magnetic resonance letters · 2023Article
- Ultrafast transverse relaxation exchange NMR spectroscopy.Physical chemistry chemical physics : PCCP · 2022Article
- A Field-Independent Method for the Rapid Generation of Hyperpolarized [1-Angewandte Chemie (International ed. in English) · 2022Article
- Sensitive, Efficient and Portable Analysis of Molecular Exchange Processes by Hyperpolarized Ultrafast NMR.Angewandte Chemie (International ed. in English) · 2022Article
- Combined diffusion-relaxometry microstructure imaging: Current status and future prospects.Magnetic resonance in medicine · 2021Review
- Ultrafast Laplace NMR to study metal-ligand interactions in reversible polarisation transfer from parahydrogen.Physical chemistry chemical physics : PCCP · 2021Article
- Ultrafast 2DChemical communications (Cambridge, England) · 2021Article
- High-Resolution Reconstruction for Multidimensional Laplace NMR.The journal of physical chemistry letters · 2021Article
- Identification of extracellular nanoparticle subsets by nuclear magnetic resonance.Chemical science · 2021Article
- Article
- Accelerating Restricted Diffusion NMR Studies with Time-Resolved and Ultrafast Methods.Analytical chemistry · 2020Article
- Ultrafast diffusion exchange nuclear magnetic resonance.Nature communications · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditional nuclear magnetic resonance (NMR) spectroscopy relies on the versatile chemical information conveyed by spectra. To complement conventional NMR, Laplace NMR explores diffusion and relaxation phenomena to reveal details on molecular motions. Under a broad concept of ultrafast multidimensional Laplace NMR, here we introduce an ultrafast diffusion-relaxation correlation experiment enhancing the resolution and information content of corresponding 1D experiments as well as reducing the experiment time by one to two orders of magnitude or more as compared with its conventional 2D counterpart. We demonstrate that the method allows one to distinguish identical molecules in different physical environments and provides chemical resolution missing in NMR spectra. Although the sensitivity of the new method is reduced due to spatial encoding, the single-scan approach enables one to use hyperpolarized substances to boost the sensitivity by several orders of magnitude, significantly enhancing the overall sensitivity of multidimensional Laplace NMR.
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Registered trials
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