Evidence map›Paper›PMID 26380366›Full record

Trial reportTheScientificWorldJournal2015

Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial.

R Casañas, R Catalán, R Penadés, J Real, S Valero, Ma Muñoz, Ll Lalucat-Jo, M Casas

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in TheScientificWorldJournal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

R CasañasResearch Department, Centre Higiene Mental (CHM) Les Corts, C/Numancia, 103-105 Bajos, 08029 Barcelona, Spain ; Psychiatry and Legal Medicine Department, Universidad Autónoma de Barcelona, Barcelona, Spain ; Primary Healthcare University Research Institute IDIAP-Jordi Gol, Institut Català de la Salut (ICS), C/Sardenya 375, 08036 Barcelona, Spain.
R CatalánClinical Institute of Neurosciences (ICN), Hospital Clinic, Barcelona, Spain ; Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Barcelona, Spain ; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain ; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, Spain.
R PenadésClinical Institute of Neurosciences (ICN), Hospital Clinic, Barcelona, Spain ; Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Barcelona, Spain ; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain ; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, Spain.
J RealPrimary Healthcare University Research Institute IDIAP-Jordi Gol, Institut Català de la Salut (ICS), C/Sardenya 375, 08036 Barcelona, Spain.
S ValeroCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, Spain ; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Universidad Autónoma de Barcelona (UAB), Barcelona, Spain.
Ma MuñozPrimary Healthcare University Research Institute IDIAP-Jordi Gol, Institut Català de la Salut (ICS), C/Sardenya 375, 08036 Barcelona, Spain.
Ll Lalucat-JoResearch Department, Centre Higiene Mental (CHM) Les Corts, C/Numancia, 103-105 Bajos, 08029 Barcelona, Spain.
M CasasCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, Spain ; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Universidad Autónoma de Barcelona (UAB), Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD) medication may interfere with the effects of the intervention.

methods106 participants were included, 50 from the PE program (12 weekly 1.5-hour sessions) and 56 from the control group (CG) that received the usual care. Patients were assessed at baseline and at 3, 6, and 9 months. The main outcome measures were the Beck Depression Inventory (BDI) and remission based on the BDI. The analysis was carried out on an intention-to-treat basis.

resultsThe PE program group showed remission of symptoms of 40% (P = 0.001) posttreatment and 42% (P = 0.012) at 6 months. The analysis only showed significant differences in the BDI score posttreatment (P = 0.008; effect size Cohen's d' = 0.55).

conclusionsThe PE intervention is an effective treatment in the depressive population not treated with AD medication. Before taking an AD, psychoeducational intervention should be considered.

Indexed as

Cognitive Behavioral TherapyAdultAgedAntidepressive AgentsCognitionDepressionFemaleHumansMaleMiddle AgedPersonality InventoryPrimary Health CarePsychiatric Status Rating ScalesTreatment OutcomeAntidepressive Agents

Identifiers

PMID26380366
PMCPMC4562075

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.