Evidence map›Paper›PMID 26380337›Full record

ArticleOpen forum infectious diseases2015

Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy.

Darrell H S Tan, Leah Szadkowski, Janet Raboud, Tae Joon Yi, Brett Shannon, Rupert Kaul, W Conrad Liles, Sharon Walmsley

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Darrell H S TanDepartments of Medicine ; Division of Infectious Diseases , St. Michael's Hospital ; Division of Infectious Diseases ; Toronto General Research Institute , University Health Network , Ontario, Canada.
Leah SzadkowskiToronto General Research Institute , University Health Network , Ontario, Canada.
Janet RaboudDalla Lana School of Public Health , University of Toronto ; Toronto General Research Institute , University Health Network , Ontario, Canada.
Tae Joon YiImmunology.
Brett ShannonImmunology.
Rupert KaulDepartments of Medicine ; Immunology ; Division of Infectious Diseases ; Toronto General Research Institute , University Health Network , Ontario, Canada.
W Conrad LilesDepartment of Medicine , University of Washington , Seattle.
Sharon WalmsleyDepartments of Medicine ; Division of Infectious Diseases ; Toronto General Research Institute , University Health Network , Ontario, Canada.
Office of Infectious Diseases · USUniversity Health Network · CAUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We used generalized estimating equations to quantify the impact of recent vaccination or intercurrent infections on immune and inflammatory biomarkers among 144 human immunodeficiency virus (HIV)-infected adults with HIV RNA < 50 copies/mL on antiretroviral therapy. These events were associated with a 2.244 µg/mL increase in high sensitivity C-reactive protein and should be routinely assessed in future studies.

Indexed as

C-reactive proteinHIVimmune activationinfectionsinflammatory biomarkersvaccinations

Identifiers

PMID26380337
PMCPMC4567101
OpenAlexW2035146728

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.