Evidence map›Paper›PMID 26380333›Full record

ArticleOpen forum infectious diseases2015

Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1.

David Sibon, Olivier Cassar, Isabelle Duga, Chantal Brouzes, David Ghez, Christophe Pasquier, Claire Sibon, Alexandra Desrames, Franck Mortreux, Eric Wattel and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

David SibonHématologie Adulte , Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris ; Institut National de la Santé et de la Recherche Médicale (INSERM) U1163 and Centre National de la Recherche Scientifique (CNRS) ERL 8254 Bases Cellulaires et Moléculaires des Désordres Hématologiques ; Institut Imagine, Université Paris Descartes-Sorbonne Paris Cité
Olivier CassarDépartement de Virologie , Institut Pasteur, Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes ; CNRS UMR 3569, Institut Pasteur.
Isabelle DugaDépartement de Pathologie , Hôpital Purpan , Toulouse.
Chantal BrouzesLaboratoire d'Hématologie , Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris.
David GhezHématologie , Institut Gustave-Roussy , Villejuif.
Christophe PasquierLaboratoire de Virologie , Hôpital Purpan , Toulouse.
Claire SibonDépartement de Dermatologie , Hôpital Ambroise-Paré , Boulogne-Billancourt.
Alexandra DesramesDépartement de Virologie , Institut Pasteur, Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes ; CNRS UMR 3569, Institut Pasteur.
Franck MortreuxLaboratoire d'Oncovirologie et Biothérapies , CNRS UMR 5239, Centre Hospitalier Lyon Sud , France.
Eric WattelLaboratoire d'Oncovirologie et Biothérapies , CNRS UMR 5239, Centre Hospitalier Lyon Sud , France.
Ali BazarbachiDepartment of Internal Medicine , American University of Beirut , Lebanon.
Antoine GessainDépartement de Virologie , Institut Pasteur, Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes ; CNRS UMR 3569, Institut Pasteur.
Olivier HermineHématologie Adulte , Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris ; Institut National de la Santé et de la Recherche Médicale (INSERM) U1163 and Centre National de la Recherche Scientifique (CNRS) ERL 8254 Bases Cellulaires et Moléculaires des Désordres Hématologiques ; Institut Imagine, Université Paris Descartes-Sorbonne Paris Cité
Institut Pasteur · FRDélégation Paris 5 · FRHôpital Purpan · FRUniversité Claude Bernard Lyon 1 · FRAmerican University of Beirut · LBHôpital Ambroise-Paré · FRHôpital Necker-Enfants Malades · FRInstitut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult T-cell leukemia/lymphoma (ATLL), a T-cell neoplasm caused by human T-cell lymphotropic virus type 1 (HTLV-1), develops in the majority of cases in individuals who were infected with HTLV-1 as young children, by their mother during prolonged breastfeeding. We report the case of a Caucasian French man, whose parents were HTLV-1-seronegative and who developed ATLL after HTLV-1 sexual transmission by a Cameroonian woman. This hypothesis was corroborated by genotyping of the patient's virus, which revealed an HTLV-1B strain, found only in Central Africa, especially in Cameroon. Thus, ATLL may develop after HTLV-1 infection during adulthood, outside breastfeeding.

Indexed as

ATLLHTLV-1HTLV-1 transmissionlymphomaviral genotyping

Identifiers

PMID26380333
PMCPMC4567067
OpenAlexW2144907676

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.