Evidence map›Paper›PMID 26380292›Full record

ArticleBioMed research international2015

Risk Factors for Development of Septic Shock in Patients with Urinary Tract Infection.

Chih-Yen Hsiao, Huang-Yu Yang, Chih-Hsiang Chang, Hsing-Lin Lin, Chao-Yi Wu, Meng-Chang Hsiao, Peir-Haur Hung, Su-Hsun Liu, Cheng-Hao Weng, Cheng-Chia Lee and 3 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04108910 (Reduction in Morbidity Rate for Urinary Tract Infections Through Use of PCR-Based Diagnosis and Management), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04108910 completednot on this mapstarted 2016, after this paper: background citation

Reduction in Morbidity Rate for Urinary Tract Infections Through Use of PCR-Based Diagnosis and Management

TypeobservationalSponsorPathnosticsRan2016 to 2020Enrolled66,381ConditionsUrinary Tract InfectionsArmsGuidance UTI
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

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  6. Analysis of SGLT2 Inhibitor Therapy and Other Potential Risk Factors for the Development of Bacteremia in Patients With Urosepsis.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Chih-Yen HsiaoDepartment of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi, Taiwan ; Department of Hospital and Health Care Administration, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.
Huang-Yu YangDepartment of Nephrology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chih-Hsiang ChangDepartment of Nephrology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Hsing-Lin LinDepartment of Emergency, FooYin University Hospital, Pingtung County, Taiwan ; Department of Nurse, Tajen University, Pingtung, Taiwan.
Chao-Yi WuDivision of Allergy, Asthma, and Rheumatology, Departmen of Pediatrics, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Meng-Chang HsiaoDepartment of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.
Peir-Haur HungDepartment of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi, Taiwan ; Department of Applied Life Science and Health, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.
Su-Hsun LiuDepartment of Family Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Cheng-Hao WengDepartment of Nephrology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Cheng-Chia LeeDepartment of Nephrology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Tzung-Hai YenDepartment of Nephrology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yung-Chang ChenDepartment of Nephrology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Tzu-Chin WuDivision of Chest, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan ; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Chang Gung University · TWChia-Yi Christian Hospital · TWChung Shan Medical University Hospital · TWTajen University · TWUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSevere sepsis and septic shock are associated with substantial mortality. However, few studies have assessed the risk of septic shock among patients who suffered from urinary tract infection (UTI). MATERIALS AND

methodsThis retrospective study recruited UTI cases from an acute care hospital between January 2006 and October 2012 with prospective data collection.

resultsOf the 710 participants admitted for UTI, 80 patients (11.3%) had septic shock. The rate of bacteremia is 27.9%; acute kidney injury is 12.7%, and the mortality rate is 0.28%. Multivariable logistic regression analyses indicated that coronary artery disease (CAD) (OR: 2.521, 95% CI: 1.129-5.628, P = 0.024), congestive heart failure (CHF) (OR: 4.638, 95% CI: 1.908-11.273, P = 0.001), and acute kidney injury (AKI) (OR: 2.992, 95% CI: 1.610-5.561, P = 0.001) were independently associated with septic shock in patients admitted with UTI. In addition, congestive heart failure (female, OR: 4.076, 95% CI: 1.355-12.262, P = 0.012; male, OR: 5.676, 95% CI: 1.103-29.220, P = 0.038, resp.) and AKI (female, OR: 2.995, 95% CI: 1.355-6.621, P = 0.007; male, OR: 3.359, 95% CI: 1.158-9.747, P = 0.026, resp.) were significantly associated with risk of septic shock in both gender groups.

conclusionThis study showed that patients with a medical history of CAD or CHF have a higher risk of shock when admitted for UTI treatment. AKI, a complication of UTI, was also associated with septic shock. Therefore, prompt and aggressive management is recommended for those with higher risks to prevent subsequent treatment failure in UTI patients.

Indexed as

Acute Kidney InjuryAdultAgedBacteremiaFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsShock, SepticUrinary Tract Infections

Identifiers

PMID26380292
PMCPMC4561874
OpenAlexW1559439200

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.