ReviewNeural plasticity2015
Behavioral Tagging: A Translation of the Synaptic Tagging and Capture Hypothesis.
Review in Neural plasticity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05150951 (An Attempt at Translating Novelty-enhanced Extinction of Context Conditioning From Rodents to Humans), which is not on this map. Cited by 63 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Attempt at Translating Novelty-enhanced Extinction of Context Conditioning From Rodents to Humans
Who cites it
63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- Salient experiences enhance mundane memories through graded prioritization.Science advances · 2025Pooled it
- Is there selective retroactive memory enhancement in humans?: a meta-analysis.Psychonomic bulletin & review · 2024Pooled it
- Reward-enhanced encoding improves relearning of forgotten associations.Scientific reports · 2018Trial
- Generalisation between motor and declarative memory sequences: A conceptual replication of Mosha & Robertson (2016).iScience · 2026Article
- From Erythropoiesis to Circuit Rewiring: Erythropoietin as a Precision Tool for Neurorestoration.International journal of molecular sciences · 2026Review
- Emotional learning selectively distorts the temporal organization of memory: A quantitative synthesis.Cognition · 2026Article
- Rodents' episodic-like memory: concepts, ageing, neurodegeneration, future.Translational neuroscience · 2026Article
- Prediction Error-Related Memory Enhancement Depends on the Neural State Surrounding the Prediction Error Event.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Molecular Substrates of Second-Order Conditioned Fear in the Basolateral Amygdala Complex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Mapping the hippocampal spatial proteomic signature in male and female mice of an early Alzheimer's disease model.Biology of sex differences · 2025Article
- Evidence for indirect strengthening through reactivation of contextually bound memories.Communications psychology · 2025Article
- Beyond boundaries: extended temporal flexibility in synaptic tagging and capture.Communications biology · 2025Article
- Impact of spindle-inspired transcranial alternating current stimulation during a nap on sleep-dependent motor memory consolidation in healthy older adults.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical protein kinase C in the anterior cingulate cortex.Neuroscience · 2025Article
- Experience-driven competition in neural reorganization after stroke.The Journal of physiology · 2025Review
- Memory persistence enhancement by post-learning moderate exercise requires de novo protein synthesis in the dorsal hippocampus.PloS one · 2025Article
- Stress enhances memory for previously encoded events depending on stressor recall.Learning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- Predatory Odor Exposure as a Potential Paradigm for Studying Emotional Modulation of Memory Consolidation-The Role of the Noradrenergic Transmission in the Basolateral Amygdala.International journal of molecular sciences · 2024Article
- Potential interactive effect of positive expectancy violation and sleep on memory consolidation in dogs.Scientific reports · 2024Article
- Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Similar molecular machinery is activated in neurons following an electrical stimulus that induces synaptic changes and after learning sessions that trigger memory formation. Then, to achieve perdurability of these processes protein synthesis is required for the reinforcement of the changes induced in the network. The synaptic tagging and capture theory provided a strong framework to explain synaptic specificity and persistence of electrophysiological induced plastic changes. Ten years later, the behavioral tagging hypothesis (BT) made use of the same argument, applying it to learning and memory models. The hypothesis postulates that the formation of lasting memories relies on at least two processes: the setting of a learning tag and the synthesis of plasticity related proteins, which once captured at tagged sites allow memory consolidation. BT explains how weak events, only capable of inducing transient forms of memories, can result in lasting memories when occurring close in time with other behaviorally relevant experiences that provide proteins. In this review, we detail the findings supporting the existence of BT process in rodents, leading to the consolidation, persistence, and interference of a memory. We focus on the molecular machinery taking place in these processes and describe the experimental data supporting the BT in humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.