ArticleOpen heart
Impact of frailty on outcomes after percutaneous coronary intervention: a prospective cohort study.
Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- Frailty Predicts Poor Prognosis of Patients After Percutaneous Coronary Intervention: A Meta-Analysis of Cohort Studies.Frontiers in medicine · 2021Pooled it
- Characteristics and Outcomes of Older Patients Undergoing Protected Percutaneous Coronary Intervention With Impella.Journal of the American Heart Association · 2025Trial
- Beyond Chronological Age: Frailty, Vulnerability, and Invasive Decision-Making in Older Adults with Acute Coronary Syndromes.Geriatrics (Basel, Switzerland) · 2026Review
- Association between frailty and long-term outcomes in patients undergoing TAVI admitted to private intensive care units in Australia.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- Frailty scale with the best prediction of mortality in individuals diagnosed with acute coronary syndrome: systematic review and meta-analysis.Journal of geriatric cardiology : JGC · 2026Article
- Latent profile analysis and associated factors of kinesophobia in patients with hip fractures.BMC psychology · 2026Observational
- Association Between Frailty and Leptin Levels in Patients with Stable Coronary Artery Disease.Diagnostics (Basel, Switzerland) · 2026Article
- Frailty status and outcomes of percutaneous coronary intervention in elderly patients with non-ST-elevation myocardial infarction.World journal of cardiology · 2025Article
- Association of Frailty With Readmissions and Outcomes After Impella Mechanical Circulatory Support.CJC open · 2025Article
- Epigenetic Biomarkers of Cardiovascular Risk in Frail Patients-A Scope Review.Current issues in molecular biology · 2025Review
- Development and validation of risk-predicting model for oral frailty in older adults patients with stroke.BMC oral health · 2025Article
- Frailty as an independent predictor for midterm adverse outcomes in the elderly undergoing primary percutaneous coronary intervention: A longitudinal cohort study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Observational
- Risk of Atherosclerotic Cardiovascular Disease After Chronic Obstructive Pulmonary Disease Hospitalization among Primary and Secondary Prevention Older Adults.Journal of the American Heart Association · 2025Article
- Predictive Value of Inflammation Markers for Frailty in Older Patients with CVD.Clinical interventions in aging · 2025Article
- Development and validation of machine learning-derived frailty index in predicting outcomes of patients undergoing percutaneous coronary intervention.International journal of cardiology. Heart & vasculature · 2024Article
- Impact of Frailty on Early Readmissions of Endoscopic Retrograde Cholangiopancreatography in the United States: Where Do We Stand?Journal of clinical medicine · 2024Article
- Frailty and In-Hospital Outcomes for Management of Cardiogenic Shock without Acute Myocardial Infarction.Journal of clinical medicine · 2024Article
- An analysis of influencing factors of oral frailty in the elderly in the community.BMC oral health · 2024Article
- Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis.World journal of clinical cases · 2024Article
- Pre-existing frailty in the elderly and long-term mortality following percutaneous coronary intervention.Journal of geriatric cardiology : JGC · 2023Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAverage life expectancy is rising, resulting in increasing numbers of elderly, frail individuals presenting with coronary artery disease and requiring percutaneous coronary intervention (PCI). PCI can be of value for this population, but little is known about the balance of benefit versus risk, particularly in the frail.
objectiveTo determine the relationship between frailty and clinical outcomes in patients undergoing PCI.
methodsPatients undergoing PCI, for either stable angina or acute coronary syndrome, were prospectively assessed for frailty using the Canadian Study of Health and Ageing Clinical Frailty Scale. Demographics, clinical and angiographic data were extracted from the hospital database. Mortality was obtained from the Office of National Statistics.
resultsFrailty was assessed in 745 patients undergoing PCI. The mean age of patients was 62±12 years and 70% were males. The median frailty score was 3 (IQR 2-4). A frailty score ≥5, indicating significant frailty, was present in 81 (11%) patients. Frail patients required longer hospitalisation after PCI. Frailty was also associated with increased 30-day (HR 4.8, 95% CI 1.4 to 16.3, p=0.013) and 1 year mortality (HR 5.9, 95% CI 2.5 to 13.8, p<0.001). Frailty was a predictor of length of hospital stay and mortality, independent of age, gender and comorbidities.
conclusionsA simple assessment of frailty can help predict mortality and the length of hospital stay, and may therefore guide healthcare providers to plan PCI and appropriate resources for frail patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.