Evidence map›Paper›PMID 26380019›Full record

ArticleInternational journal of clinical and experimental medicine2015

Quantitative analysis of suspicious thyroid nodules by contrast-enhanced ultrasonography.

Yizhou Hu, Ping Li, Shufei Jiang, Fenghua Li

Abstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yizhou HuDepartment of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiaotong University Shanghai 200127, China.
Ping LiDepartment of Tumor Interventional Treatment, Renji Hospital, School of Medicine, Shanghai Jiaotong University Shanghai 200127, China.
Shufei JiangDepartment of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiaotong University Shanghai 200127, China.
Fenghua LiDepartment of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiaotong University Shanghai 200127, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the characteristics of suspicious thyroid nodules of different pathological types on contrast-enhanced ultrasound (CEUS) with quantitative analysis software (Qlab).

methodsA total of 101 suspicious thyroid nodules were recruited from 90 adult patients undergoing ultrasound (US), CEUS and fine-needle aspiration cytology (FNCA). The CEUS characteristics were quantitatively analyzed by investigators blind to the pathological information.

resultsIn 68 benign thyroid nodules, the proportion of single nodules was higher (54.4%) than that of miliary nodules (n = 2-4), and most of them were identical-in, slow-out and hypoenhancement as compared to adjacent normal tissues. In 17 malignant thyroid nodules, most of them were slow-in, identical-out and more hypoenhancement as compared to adjacent normal tissues on CEUS.

conclusionBenign thyroid nodules show identical-in, slow-out and hypoenhancement while malignant thyroid nodules have slow-in, identical-out and more hypoenhancement as compared to adjacent normal tissues on CEUS. Quantitative analysis of thyroid nodules on CEUS may help to identify suspicious nodules and select a proper treatment.

Indexed as

contrast-enhanced ultrasoundSuspicious thyroid nodules

Identifiers

PMID26380019
PMCPMC4565402

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.