ArticleInternational journal of clinical and experimental medicine2015
Effect of obesity and hyperglycemia on benign prostatic hyperplasia in elderly patients with newly diagnosed type 2 diabetes.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Risk of BPH-LUTS according to the PM₁₀ exposure: A longitudinal nationwide cohort-based study.Investigative and clinical urology · 2026Article
- Association between insulin resistance and prostate volume: A 4-year analysis from the Reduction by Dutasteride of Prostate Cancer (REDUCE) Trial.BJUI compass · 2025Article
- SGLT2 Inhibitors in Patients with Urogenital Malformations and Urinary Diversions: Risks, Benefits, and Clinical Considerations.Medicina (Kaunas, Lithuania) · 2025Review
- Risk of poor glycemic control in tamsulosin versus finasteride users with type 2 diabetes mellitus.Heliyon · 2025Article
- Capsaicin reduces blood glucose and prevents prostate growth by regulating androgen, RAGE/IGF-1/Akt, TGF-β/Smad signalling pathway and reversing epithelial-mesenchymal transition in streptozotocin-induced diabetic mice.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Association between dietary niacin intake and benign prostatic hyperplasia: a population-based results from NHANES 2003-2008.Journal of health, population, and nutrition · 2024Article
- Intrinsic and extrinsic factors causing hyperplasia of the prostate.International journal of urology : official journal of the Japanese Urological Association · 2024Review
- Overview of BPH: Symptom Relief with Dietary Polyphenols, Vitamins and Phytochemicals by Nutraceutical Supplements with Implications to the Prostate Microbiome.International journal of molecular sciences · 2023Review
- Lipidic extract of whole tomato reduces hyperplasia, oxidative stress and inflammation on testosterone-induced BPH in obese rats.International urology and nephrology · 2023Article
- A synchronous spectrofluorometric technique for simultaneous detection of alfuzosin and tadalafil: applied to tablets and spiked biological samples.Royal Society open science · 2022Article
- Serum testosterone and prostate-specific antigen levels are major risk factors for prostatic volume increase among benign prostatic hyperplasia patients.Asian journal of urology · 2021Article
- Correlation between body mass index and prostate volume in benign prostatic hyperplasia patients undergoing holmium enucleation of the prostate surgery.BMC urology · 2021Article
- The preventive effect of metformin on progression of benign prostate hyperplasia: A nationwide population-based cohort study in Korea.PloS one · 2019Article
- High glucose induces the proliferation of prostatic cells via downregulating MRE11.International journal of molecular medicine · 2018Article
- Correlation of self-reported urologic symptoms with systemic health conditions in minority men.Translational andrology and urology · 2017Article
- Is there room for behavioral and modifiable health-related targets in the lower urinary tract symptoms' scenario.World journal of urology · 2017Article
- Article
- Body Mass Index and Risk of Prostate Volume, International Prostate Symptom Score, Maximum Urinary Flow Rate, and Post-Void Residual in Benign Prostatic Hyperplasia Patients.American journal of men's healthArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the relationship between blood glucose levels, age, body mass index (BMI), and benign prostatic hyperplasia (BPH) in patients with newly diagnosed type 2 diabetes.
methodsA total of 141 BPH patients with newly diagnosed type 2 diabetes participated in this study. Their glucose level, international prostate symptom score (IPSS), prostate volume (PV), and maximum urinary flow rate (Qmax) were determined and analyzed.
resultsCompared to patients in 60-69 years of age, those in 70-79 years of age had higher IPSS and PV values (11.10±2.68 vs. 16.09±2.64, respectively; P<0.01; 38.67±4.65 vs. 44.76±2.84, respectively; P<0.01) as did patients ≥80 y (11.10±2.68 vs. 19.87±3.35, respectively; P<0.01; 38.67±4.65 vs. 51.38±3.74, respectively; P<0.01). The Qmax was lower in the ≥80 y group compared to the 60-69 y group (7.91±2.13 vs. 13.50±1.75, respectively; P<0.01). IPSS, PV, and insulin resistance index (HOMA-IR) were higher in patients with a BMI ≥28 kg/m(2) group as compared to those with a BMI <24 kg/m(2) group. IPSS and PV values were higher in patients with HbA1c levels ≥6.5% than in those with HbA1c<6.5% (16.30±3.31 vs. 9.87±1.07, respectively; P<0.01; 45.69±3.97 vs. 36.64±3.30, respectively; P<0.01), and the Qmax was lower (10.61±1.98 vs. 14.40±0.82, respectively; P<0.01).
conclusionsAging, obesity, high glucose level, and insulin resistance increase the risk of BPH progression in elderly patients with newly diagnosed type 2 diabetes. Managing body weight and lowering the level of glycosylated hemoglobin may slow the progression of BPH in people with type 2 diabetes.
Indexed as
Identifiers
26379937PMC4565320W2210647361What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.