ArticleInternational journal of clinical and experimental medicine2015
The role of FDG PET/CT in evaluation of mediastinal masses and neurogenic tumors of chest wall.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Percutaneous Computed Tomography (CT)-Guided Biopsy of Focal Chest Wall Lesions: A Retrospective Cohort Study.Cureus · 2025Article
- The role of positron emission tomography in mediastinal mass.Mediastinum (Hong Kong, China) · 2025Review
- Minimally Invasive Sampling of Mediastinal Lesions.Life (Basel, Switzerland) · 2024Review
- Diagnostic modalities in the mediastinum and the role of bronchoscopy in mediastinal assessment: a narrative review.Mediastinum (Hong Kong, China) · 2024Review
- Imaging modalities (MRI, CT, PET/CT), indications, differential diagnosis and imaging characteristics of cystic mediastinal masses: a review.Mediastinum (Hong Kong, China) · 2023Review
- Resection of a giant mediastinal liposarcoma by median sternotomy with vascular reconstruction-a case report.Mediastinum (Hong Kong, China) · 2023Article
- Comparative Role of MDCT and FDG-PET/CT in the Diagnostic Evaluation of Mediastinal Mass Lesions: An Institutional Experience.World journal of nuclear medicine · 2022Article
- Comparison of VATS and Thoracotomy Results in Mediastinal Neurogenic Tumors.The Eurasian journal of medicine · 2021Article
- Evaluation of surgical procedures in primary mediastinal cysts and tumors: single-center experience.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2019Article
- Distinguishing between Thymic Epithelial Tumors and Benign Cysts via Computed Tomography.Korean journal of radiology · 2019Article
- Diagnostic approach to the anterior/prevascular mediastinum for radiologists.Mediastinum (Hong Kong, China) · 2019Review
- Assessment of paraspinal neurogenic tumors with diffusion-weighted MR imaging.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Article
- Castleman disease in the hilum liver mimicking the lymph node metastasis of hepatocellular carcinoma on 18F-FDG PET/CT: A case report.Medicine · 2018Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledWe evaluated the efficiency of FDG PET/CT for the differentiation of malignant from benign mediastinal masses and neurogenic tumors of chest-wall.
methodsThe 88 patients with chest wall-mediastinal masses who underwent examination before operation were retrospectively reviewed. Size, CT density (HU mean) and SUVmax of mediastinal and chest wall lesions were determined. Statistical differences of these parameters were compared between groups by Mann-Whitney U test. Receiver-operating characteristic curve (ROC) analysis with respect to SUVmax was performed to determine the best cutoff value for differentiating benign from malignant masses.
resultsThe overall sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of PET/CT in detection of malignancy were 90%, 55.17%, 67%, 50.94% and 91.43%, respectively. The SUVmax, HU mean and size were higher in malignant cases (P < 0.05). To distinguish benign and malignant lesions, the cut off value of SUVmax was 4.67. The lesion SUVmax was significantly associated with the lesion size and lesion HU mean values (P < 0.05). The value of SUVmax and HU mean were higher in solid benign lesions than those of cystic benign lesions (P < 0.05). The lesion size was higher in cystic lesions (P = 0.000). The mean SUVmax was significantly higher in invasive thymomas than those of non-invasive forms (P = 0.029).
conclusionFDG PET/CT may be complementary to conventional imaging methods for the evaluation of mediastinal and chest wall masses. PET/CT may reduce unnecessary invasive investigations for diagnosis in patients with nonavid or low avid FDG lesions. However confirmatory tissue sampling is required to confirm PET positive findings for the definite diagnosis.
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Identifiers
26379916PMC4565299W2408982746What OpenQuestion holds
Registered trials
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