Evidence map›Paper›PMID 26379889›Full record

ArticleInternational journal of clinical and experimental medicine2015

Value of sequential 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in prediction of the overall survival of esophageal cancer patients treated with chemoradiotherapy.

Yimin Li, Qin Lin, Zuoming Luo, Long Zhao, Luchao Zhu, Long Sun, Hua Wu

Abstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Prognostic value of baselineRadiation oncology (London, England) · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. International journal of clinical and experimental pathology · 2019
    Article
  10. Article
  11. Article
  12. Radiologia brasileira
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yimin LiDepartment of Radiation Oncology, The Xiamen First Affiliated Hospital of Xiamen University Xiamen 361003, P. R. China.
Qin LinDepartment of Radiation Oncology, The Xiamen First Affiliated Hospital of Xiamen University Xiamen 361003, P. R. China.
Zuoming LuoDepartment of Nuclear Medicine, The Xiamen First Affiliated Hospital of Xiamen University Xiamen 361003, P. R. China.
Long ZhaoDepartment of Nuclear Medicine, The Xiamen First Affiliated Hospital of Xiamen University Xiamen 361003, P. R. China.
Luchao ZhuDepartment of Radiation Oncology, The Xiamen First Affiliated Hospital of Xiamen University Xiamen 361003, P. R. China.
Long SunDepartment of Nuclear Medicine, The Xiamen First Affiliated Hospital of Xiamen University Xiamen 361003, P. R. China.
Hua WuDepartment of Nuclear Medicine, The Xiamen First Affiliated Hospital of Xiamen University Xiamen 361003, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is to investigate the value of the metabolic parameters measured by sequential FDG PET/CT in predicting the overall survival of patients with esophageal squamous cell carcinoma (ESCC). A total of 160 patients who were newly diagnosed as ESCC patients and treated with chemoradiotherapy were included in this study. The FDG PET/CT was carried out prior to radiotherapy (PET1), when the cumulative dose of radiotherapy reached 50 Gy (PET2), at the end of radiotherapy (PET3) and 1 month after radiotherapy (PET4). The max of the standard uptake value (SUVmax) of the primary tumor, the metabolic tumor volume (MTV) and the total lesion glycolisis (TLG) prior to treatment were measured. The correlation of the measured parameters and the derived parameters of SUVmax with the overall survival was analyzed. The relatively reduced percentage of the SUVmax of PET3 and PET4 to the SUVmax of PET1 and PET2, had predictive value for the overall survival. The area under researcher operation curve (ROC) was between 0.62 and 0.73 (P < 0.01). The MTV and TLG prior to treatment might be used to predict the overall survival, and the area under ROC were both 0.69 (P < 0.001). Sequential FDG PET/CT scanning is useful to predict the overall survival of chemoradiotherapy for ESCC. The metabolic parameters and the derived parameters of FDG PET/CT have predictive values for overall survival.

Indexed as

Esophageal cancerFDG PET/CTsurvival analysis

Identifiers

PMID26379889
PMCPMC4565272

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.