Evidence map›Paper›PMID 26379761›Full record

ArticleComputational and mathematical methods in medicine2015

Risk Prediction of One-Year Mortality in Patients with Cardiac Arrhythmias Using Random Survival Forest.

Fen Miao, Yun-Peng Cai, Yu-Xiao Zhang, Ye Li, Yuan-Ting Zhang

Abstract readValidation Study
In one paragraph

Article in Computational and mathematical methods in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

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20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  14. Observational
  15. Building Computational Models to Predict One-Year Mortality in ICU Patients with Acute Myocardial Infarction and Post Myocardial Infarction Syndrome.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Fen MiaoKey Laboratory for Health Informatics of the Chinese Academy of Sciences (HICAS), Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China ; Shenzhen College of Advanced Technology, University of Chinese Academy of Sciences, Beijing 100049, China.
Yun-Peng CaiKey Laboratory for Health Informatics of the Chinese Academy of Sciences (HICAS), Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China.
Yu-Xiao ZhangDepartment of Senile Cardiovascular Medicine, The General Hospital of the People's Liberation Army, Beijing 100853, China.
Ye LiKey Laboratory for Health Informatics of the Chinese Academy of Sciences (HICAS), Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China.
Yuan-Ting ZhangKey Laboratory for Health Informatics of the Chinese Academy of Sciences (HICAS), Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China ; Joint Research Centre for Biomedical Engineering, Department of Electronic Engineering, Chinese University of Hong Kong, Shatin 00852, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Existing models for predicting mortality based on traditional Cox proportional hazard approach (CPH) often have low prediction accuracy. This paper aims to develop a clinical risk model with good accuracy for predicting 1-year mortality in cardiac arrhythmias patients using random survival forest (RSF), a robust approach for survival analysis. 10,488 cardiac arrhythmias patients available in the public MIMIC II clinical database were investigated, with 3,452 deaths occurring within 1-year followups. Forty risk factors including demographics and clinical and laboratory information and antiarrhythmic agents were analyzed as potential predictors of all-cause mortality. RSF was adopted to build a comprehensive survival model and a simplified risk model composed of 14 top risk factors. The built comprehensive model achieved a prediction accuracy of 0.81 measured by c-statistic with 10-fold cross validation. The simplified risk model also achieved a good accuracy of 0.799. Both results outperformed traditional CPH (which achieved a c-statistic of 0.733 for the comprehensive model and 0.718 for the simplified model). Moreover, various factors are observed to have nonlinear impact on cardiac arrhythmias prognosis. As a result, RSF based model which took nonlinearity into account significantly outperformed traditional Cox proportional hazard model and has great potential to be a more effective approach for survival analysis.

Indexed as

AgedAged, 80 and overArrhythmias, CardiacComputer SimulationDatabases, FactualFemaleHumansMaleMiddle AgedModels, StatisticalNonlinear DynamicsPrognosisProportional Hazards ModelsRisk FactorsSurvival Analysis

Identifiers

PMID26379761
PMCPMC4562335

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.