ArticleFrontiers in microbiology2015
Responses in colonic microbial community and gene expression of pigs to a long-term high resistant starch diet.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 113 citations in OpenAlex.
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- A manually curated pig gut microbiome dataset for precision feeding.Scientific data · 2026Article
- Increasing carbohydrates or nitrogenous compounds by cecal infusion leads to an opposite influence on colonic microbiota and host metabolism in a pig model.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Untargeted metabolomics as a tool to assess the impact of dietary approaches on pig gut health: a review.Journal of animal science and biotechnology · 2025Review
- Breed-specific differences of gut microbiota and metabolomic insights into fat deposition and meat quality in Chinese Songliao Black Pig and Large White × Landrace Pig Breeds.BMC microbiology · 2025Article
- Fiber deprivation and insoluble corn-based fibrous -co-products modulate gastrointestinal mucosa-associated microbiota, extracellular matrix remodeling, and intestinal morphology in growing pigs.Journal of animal science · 2025Article
- Rumen and hindgut microbiome regulate average daily gain of preweaning Holstein heifer calves in different ways.Microbiome · 2024Article
- Lactation-related dynamics of bacterial and fungal microbiomes in feces of sows and gut colonization in suckling and newly weaned piglets.Journal of animal science · 2024Article
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- Time-restricted feeding affects colonic nutrient substrates and modulates the diurnal fluctuation of microbiota in pigs.Frontiers in microbiology · 2023Article
- Article
- Effect of feeding raw potato starch on the composition dynamics of the piglet intestinal microbiome.Animal bioscience · 2022Article
- Dietary benzoic acid and supplemental enzymes alter fiber-fermenting taxa and metabolites in the cecum of weaned pigs.Journal of animal science · 2022Article
- Effects of the increased protein level in small intestine on the colonic microbiota, inflammation and barrier function in growing pigs.BMC microbiology · 2022Article
- Article
- Resistant Potato Starch Alters the Cecal Microbiome and Gene Expression in Mice Fed a Western Diet Based on NHANES Data.Frontiers in nutrition · 2022Article
- Raw potato starch alters the microbiome, colon and cecal gene expression, and resistance toFrontiers in nutrition · 2022Article
- Co-fermented yellow wine lees byFrontiers in microbiology · 2022Article
- Impact of Feeding Postbiotics and Paraprobiotics Produced FromFrontiers in veterinary science · 2022Article
- Effects of mannan oligosaccharides and Lactobacillus mucosae on growth performance, immune response, and gut health of weanling pigs challenged with Escherichia coli lipopolysaccharides.Journal of animal science · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intake of raw potato starch (RPS) has been associated with various intestinal health benefits, but knowledge of its mechanism in a long-term is limited. The aim of this study was to investigate the effects of long-term intake of RPS on microbial composition, genes expression profiles in the colon of pigs. Thirty-six Duroc × Landrace × Large White growing barrows were randomly allocated to corn starch (CS) and RPS groups with a randomized block design. Each group consisted of six replicates (pens), with three pigs per pen. Pigs in the CS group were offered a corn/soybean-based diet, while pigs in the RPS group were put on a diet in which 230 g/kg (growing period) or 280 g/kg (finishing period) purified CS was replaced with purified RPS during a 100-day trial. Real-time PCR assay showed that RPS significantly decreased the number of total bacteria in the colonic digesta. MiSeq sequencing of the V3-V4 region of the 16S rRNA genes showed that RPS significantly decreased the relative abundance of Clostridium, Treponema, Oscillospira, Phascolarctobacterium, RC9 gut group, and S24-7-related operational taxonomic units (OTUs), and increased the relative abundance of Turicibacter, Blautia, Ruminococcus, Coprococcus, Marvinbryantia, and Ruminococcus bromii-related OTUs in colonic digesta and mucosa. Analysis of the colonic transcriptome profiles revealed that the RPS diet changed the colonic expression profile of the host genes mainly involved in immune response pathways. RPS significantly increased proinflammartory cytokine IL-1β gene expression and suppressed genes involved in lysosome. Our findings suggest that long-term intake of high resistant starch (RS) diet may result in both positive and negative roles in gut health.
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