ArticleJournal of the American Chemical Society2015
Palladium-catalyzed enantioselective 1,1-fluoroarylation of aminoalkenes.
Article in Journal of the American Chemical Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Palladium-catalyzed asymmetric carbofluorination ofChemical communications (Cambridge, England) · 2026Article
- Alkyne migratory functionalization via C(spNature communications · 2026Article
- One-Pot Formal Carboradiofluorination of Alkenes: A Toolkit for Positron Emission Tomography Imaging Probe Development.Journal of the American Chemical Society · 2023Article
- Article
- Nickel-Catalyzed 1,1-Aminoborylation of Unactivated Terminal Alkenes.ACS catalysis · 2023Article
- A Sterically Tuned Directing Auxiliary Promotes Catalytic 1,2-Carbofluorination of Alkenyl Carbonyl Compounds.Angewandte Chemie (International ed. in English) · 2023Article
- Catalytic Synthesis of 5-Fluoro-2-oxazolines: Using BFACS omega · 2022Article
- Synthesis of α,γ-Chiral Trifluoromethylated Amines through the Stereospecific Isomerization of α-Chiral Allylic Amines.Organic letters · 2022Article
- Controllable access to trifluoromethyl-containing indoles and indolines: palladium-catalyzed regioselective functionalization of unactivated alkenes with trifluoroacetimidoyl chlorides.Chemical science · 2022Article
- Palladium-catalyzed 1,1-alkynylbromination of alkenes with alkynyl bromides.Chemical science · 2021Article
- Catalytic asymmetric nucleophilic fluorination using BFNature communications · 2021Article
- A Transient Directing Group Strategy Enables Enantioselective Multicomponent Organofluorine Synthesis.Journal of the American Chemical Society · 2021Article
- Further Developments and Applications of Oxazoline-Containing Ligands in Asymmetric Catalysis.Chemical reviews · 2021Article
- A study on selective transformation of norbornadiene into fluorinated cyclopentane-fused isoxazolines.Beilstein journal of organic chemistry · 2021Article
- Walking metals: catalytic difunctionalization of alkenes at nonclassical sites.Chemical science · 2020Review
- Three-component vicinal-diarylation of alkenesChemical science · 2019Article
- Mechanistic Investigations of the Pd(0)-Catalyzed Enantioselective 1,1-Diarylation of Benzyl Acrylates.Journal of the American Chemical Society · 2017Article
- A practical and catalyst-free trifluoroethylation reaction of amines using trifluoroacetic acid.Nature communications · 2017Article
- The development and mechanistic investigation of a palladium-catalyzed 1,3-arylfluorination of chromenes.Chemical science · 2017Article
- Palladium-Catalyzed Defluorinative Coupling of 1-Aryl-2,2-Difluoroalkenes and Boronic Acids: Stereoselective Synthesis of Monofluorostilbenes.Angewandte Chemie (International ed. in English) · 2016Article
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4 authors.
Funding
Abstract
The development of an enantioselective palladium-catalyzed 1,1-fluoroarylation of unactivated aminoalkenes is described. The reaction uses arylboronic acids as the arene source and Selectfluor as the fluorine source to generate benzylic fluorides in good yields with excellent enantioselectivities. This transformation, likely proceeding through an oxidative Heck mechanism, affords 1,1-difunctionalized alkene products.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.