ArticleJournal of neurophysiology2015
Neuromuscular adjustments of gait associated with unstable conditions.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed, 134 citations in OpenAlex.
- Neuromuscular organisation and robustness of postural control in the presence of perturbations.Scientific reports · 2019Trial
- Movement Dynamics of Treadmill Running Within the Different Exercise Intensity Domains in Male Runners.European journal of sport science · 2026Article
- Age-dependent synergistic control of sit-to-stand motion.European journal of applied physiology · 2026Article
- Limb-specific modulation of muscle synergies and segmental coordination during curved running.Experimental brain research · 2026Article
- Adaptation-dependent modulation of coordinated muscle activities in human gait adaptation as revealed by tensor decomposition.iScience · 2026Article
- Enhanced ground reaction force analyses reveal injury-related Biomechanical differences in runners.Scientific reports · 2025Article
- Gait speed and incline modulate peak deceleration and timing of horizontal center of mass deceleration during double support.Biology open · 2025Article
- Muscle synergies and metabolic adaptations during perturbed walking in older adults.Scientific reports · 2025Article
- The role of physical activity in mitigating age-related changes in the neuromuscular control of gait.npj aging · 2025Article
- Exploring the cortical involvement in sensorimotor integration during early stages of independent walking.Experimental brain research · 2025Article
- Age-related differences in the modulation of muscle coordination complexity for goal-directed lateral stepping.Journal of biomechanics · 2025Article
- The effects of age and physical activity status on muscle synergies when walking down slopes.European journal of applied physiology · 2025Article
- Postural control of sway dynamics on an unstable surface reduces similarity in activation patterns of synergistic lower leg muscles.Frontiers in sports and active living · 2025Article
- Quantitative Evaluation of Stance as a Sensitive Biomarker of Postural Ataxia Development in Preclinical SCA1 Mutation Carriers.Cerebellum (London, England) · 2024Article
- Local Dynamic Stability of Trunk During Gait is Responsive to Rehabilitation in Subjects with Primary Degenerative Cerebellar Ataxia.Cerebellum (London, England) · 2024Article
- Increased trial-to-trial similarity and reduced temporal overlap of muscle synergy activation coefficients manifest during learning and with increasing movement proficiency.Scientific reports · 2024Article
- Spatiotemporal modulation of a common set of muscle synergies during unpredictable and predictable gait perturbations in older adults.The Journal of experimental biology · 2024Article
- The Lower Limb Muscle Co-Activation Map during Human Locomotion: From Slow Walking to Running.Bioengineering (Basel, Switzerland) · 2024Article
- Gait analysis, trunk movements, and electromyographic patterns after minimally invasive spine surgery for lumbar instability: An observational prospective study.World neurosurgery: X · 2024Article
- Consensus Paper: Ataxic Gait.Cerebellum (London, England) · 2023Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A compact description of coordinated muscle activity is provided by the factorization of electromyographic (EMG) signals. With the use of this approach, it has consistently been shown that multimuscle activity during human locomotion can be accounted for by four to five modules, each one comprised of a basic pattern timed at a different phase of gait cycle and the weighting coefficients of synergistic muscle activations. These modules are flexible, in so far as the timing of patterns and the amplitude of weightings can change as a function of gait speed and mode. Here we consider the adjustments of the locomotor modules related to unstable walking conditions. We compared three different conditions, i.e., locomotion of healthy subjects on slippery ground (SL) and on narrow beam (NB) and of cerebellar ataxic (CA) patients on normal ground. Motor modules were computed from the EMG signals of 12 muscles of the right lower limb using non-negative matrix factorization. The unstable gait of SL, NB, and CA showed significant changes compared with controls in the stride length, stride width, range of angular motion, and trunk oscillations. In most subjects of all three unstable conditions, >70% of the overall variation of EMG waveforms was accounted for by four modules that were characterized by a widening of muscle activity patterns. This suggests that the nervous system adopts the strategy of prolonging the duration of basic muscle activity patterns to cope with unstable conditions resulting from either slippery ground, reduced support surface, or pathology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.