ArticleThe international journal of behavioral nutrition and physical activity2015
Impact of physical activity, sedentary behaviour and muscle strength on bone stiffness in 2-10-year-old children-cross-sectional results from the IDEFICS study.
Article in The international journal of behavioral nutrition and physical activity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 8 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 8 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Sex Differences in Grip Strength From Birth to Age 16: A Meta-Analysis.European journal of sport science · 2025Pooled it
- Association between sedentary behavior and bone mass, microstructure and strength in children, adolescents and young adults: a systematic review.BMC public health · 2024Pooled it
- A comparison of the associations between bone health and three different intensities of accelerometer-derived habitual physical activity in children and adolescents: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Pooled it
- Measurement of screen time among young children aged 0-6 years: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Pooled it
- Screen Time and Bone Status in Children and Adolescents: A Systematic Review.Frontiers in pediatrics · 2021Pooled it
- Systematic review of the relationships between physical activity and health indicators in the early years (0-4 years).BMC public health · 2017Pooled it
- Systematic review of the relationships between sedentary behaviour and health indicators in the early years (0-4 years).BMC public health · 2017Pooled it
- Sedentary behaviour and bone health in children, adolescents and young adults: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Pooled it
- Effects of different game-based physical activity programs on body composition in Chinese preschool children.Frontiers in public health · 2025Trial
- Modifying bone mineral density, physical function, and quality of life in children with acute lymphoblastic leukemia.Pediatric blood & cancer · 2018Trial
- Does a Validated Circum-menarcheal Arm Bone-Loading Index Predict Post-menarcheal Muscle Function in Adolescent Females?Journal of musculoskeletal & neuronal interactions · 2026Article
- Types and Frequencies of Physical Activity Associated with Physical Fitness in Chinese Children and Adolescents: A National Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- The Impact of Sedentary Behavior and Physical Activity on Bone Health: A Narrative Review from the Rehabilitation Working Group of the International Osteoporosis Foundation.Calcified tissue international · 2025Review
- Accelerometer based independent and combined associations of physical activity and sedentary time on physical fitness in preschool children: a cross-sectional study.Scientific reports · 2025Article
- Comparison of physical activity, sedentary time, and physical fitness among Chinese children and adolescents in Qinghai between 2019 and 2023.Scientific reports · 2025Article
- The Cross-Sectional and Longitudinal Associations Between Adherence to 24-Hour Movement Behavior Guidelines and Bone Health in Young Children.Healthcare (Basel, Switzerland) · 2024Article
- Can physical activity counteract the negative effects of sedentary behavior on the physical and mental health of children and adolescents? A narrative review.Frontiers in public health · 2024Review
- Associations of Morphological Changes in Skeletal Muscles of Preschool Children in China Following Physical Activity.Children (Basel, Switzerland) · 2023Article
- Relationship between Skeletal Muscle Thickness and Physical Activity in 4- to 6-Year-Olds in Japan.Children (Basel, Switzerland) · 2023Article
- Is it important to achieve physical activity recommendations at early stages of life to improve bone health?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
Corrections and comments
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Authors and funding
12 authors at 10 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhysical activity (PA), weight-bearing exercises (WBE) and muscle strength contribute to skeletal development, while sedentary behaviour (SB) adversely affects bone health. Previous studies examined the isolated effect of PA, SB or muscle strength on bone health, which was usually assessed by x-ray methods, in children. Little is known about the combined effects of these factors on bone stiffness (SI) assessed by quantitative ultrasound. We investigated the joint association of PA, SB and muscle strength on SI in children.
methodsIn 1512 preschool (2- < 6 years) and 2953 school children (6-10 years), data on calcaneal SI as well as on accelerometer-based sedentary time (SED), light (LPA), moderate (MPA) and vigorous PA (VPA) were available. Parents reported sports (WBE versus no WBE), leisure time PA and screen time of their children. Jumping distance and handgrip strength served as indicators for muscle strength. The association of PA, SB and muscle strength with SI was estimated by multivariate linear regression, stratified by age group. Models were adjusted for age, sex, country, fat-free mass, daylight duration, consumption of dairy products and PA, or respectively SB.
resultsMean SI was similar in preschool (79.5 ± 15.0) and school children (81.3 ± 12.1). In both age groups, an additional 10 min/day in MPA or VPA increased the SI on average by 1 or 2%, respectively (p ≤ .05). The negative association of SED with SI decreased after controlling for MVPA. LPA was not associated with SI. Furthermore, participation in WBE led to a 3 and 2% higher SI in preschool (p = 0.003) and school children (p < .001), respectively. Although muscle strength significantly contributed to SI, it did not affect the associations of PA with SI. In contrast to objectively assessed PA, reported leisure time PA and screen time showed no remarkable association with SI.
conclusionThis study suggests that already an additional 10 min/day of MPA or VPA or the participation in WBE may result in a relevant increase in SI in children, taking muscle strength and SB into account. Our results support the importance of assessing accelerometer-based PA in large-scale studies. This may be important when deriving dose-response relationships between PA and bone health in children.
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