Evidence map›Paper›PMID 26377516›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2016

Predictive and External Validity of a Pre-Market Study to Determine the Most Effective Pictorial Health Warning Label Content for Cigarette Packages.

Li-Ling Huang, James F Thrasher, Jessica L Reid, David Hammond

Abstract readValidation Study
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Systematic Review of Measures Used in Pictorial Cigarette Pack Warning Experiments.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Pooled it
  2. Trial
  3. Combining Inserts With Warning Labels on Cigarette Packs to Promote Smoking Cessation: A 2-Week Randomized Trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024
    Trial
  4. Trial
  5. Trial
  6. Potential Effectiveness of Pictorial Warning Labels That Feature the Images and Personal Details of Real People.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Trial
  7. The Role of Harm Visibility for Pictorial Health Warning Labels on Cigars.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Are the Same Health Warnings Effective Across Different Countries? An Experimental Study in Seven Countries.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cigarette flavors, package shape, and cigarette brand perceptions: an experiment among young Brazilian women.Revista panamericana de salud publica = Pan American journal of public health · 2018
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Li-Ling HuangDepartment of Health Promotion, Education and Behavior, University of South Carolina, Columbia, SC; Center for Regulatory Research on Tobacco Communication, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC; huangl@email.unc.edu.
James F ThrasherDepartment of Health Promotion, Education and Behavior, University of South Carolina, Columbia, SC; Department of Tobacco Research, National Institute of Public Health, Cuernavaca, Mexico;
Jessica L ReidPropel Centre for Population Health Impact, University of Waterloo, Waterloo, ON, Canada;
David HammondSchool of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada.

Funding

Variation in Cigarettes, Tobacco use Behaviors and Exposures in ITC CountriesP01CA138389 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI THOMPSON, MARY · 2009 to 2013
$13.4M
Building evidence for effective and sustainable cigarette warning label policyR01CA167067 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI THRASHER, JAMES · 2012 to 2016
$2.7M
CIHRNCI NIH HHS P01 CA138389NCI NIH HHS R01 CA167067
6 · The paper itself

Abstract

introductionStudies examining cigarette package pictorial health warning label (HWL) content have primarily used designs that do not allow determination of effectiveness after repeated, naturalistic exposure. This research aimed to determine the predictive and external validity of a pre-market evaluation study of pictorial HWLs.

methodsData were analyzed from: (1) a pre-market convenience sample of 544 adult smokers who participated in field experiments in Mexico City before pictorial HWL implementation (September 2010); and (2) a post-market population-based representative sample of 1765 adult smokers in the Mexican administration of the International Tobacco Control Policy Evaluation Survey after pictorial HWL implementation. Participants in both samples rated six HWLs that appeared on cigarette packs, and also ranked HWLs with four different themes. Mixed effects models were estimated for each sample to assess ratings of relative effectiveness for the six HWLs, and to assess which HWL themes were ranked as the most effective.

resultsPre- and post-market data showed similar relative ratings across the six HWLs, with the least and most effective HWLs consistently differentiated from other HWLs. Models predicting rankings of HWL themes in post-market sample indicated: (1) pictorial HWLs were ranked as more effective than text-only HWLs; (2) HWLs with both graphic and "lived experience" content outperformed symbolic content; and, (3) testimonial content significantly outperformed didactic content. Pre-market data showed a similar pattern of results, but with fewer statistically significant findings.

conclusionsThe study suggests well-designed pre-market studies can have predictive and external validity, helping regulators select HWL content.

Indexed as

Smoking PreventionTobacco ProductsAdolescentAdultFemaleHumansLinear ModelsMaleMexicoMiddle AgedProduct LabelingPublic PolicySurveys and QuestionnairesYoung Adult

Identifiers

PMID26377516
PMCPMC5942614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.