Evidence map›Paper›PMID 26377100›Full record

ArticlePediatric cardiology2016

High Overweight and Obesity in Fontan Patients: A 20-Year History.

Stephanie T Chung, Borah Hong, Lance Patterson, Christopher J Petit, J Nina Ham

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Overweight and Obesity in Patients with Congenital Heart Disease: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Body Mass Index Trajectory and Outcome Post Fontan Procedure.Journal of the American Heart Association · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Cardiometabolic risk in obese children.Annals of the New York Academy of Sciences · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Stephanie T ChungDepartment of Pediatrics, Pediatric Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA. chungst@niddk.nih.gov.
Borah HongDepartment of Pediatrics, Cardiology, Baylor College of Medicine, Houston, TX, USA.
Lance PattersonDepartment of Pediatrics, Cardiology, Baylor College of Medicine, Houston, TX, USA.
Christopher J PetitDepartment of Pediatrics, Cardiology, Baylor College of Medicine, Houston, TX, USA.
J Nina HamDepartment of Pediatrics, Pediatric Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · USEmory University · USSeattle Children's Hospital · US

Funding

Intramural NIH HHS Z99 DK999999
6 · The paper itself

Abstract

The prevalence of obesity in long-term survivors with complex congenital heart disease may be increasing, and little is known about the timing and onset of weight gain and growth patterns in these high-risk patients. Prevalence rates of overweight/obesity and longitudinal changes in body mass index (BMI) with age were determined in 606 patients with Fontan circulation seen at a tertiary care cardiology center from 1992 to 2012. The number of clinic encounters (n) was stratified by age group (n = 401, 2-5 years; n = 333, 6-11 years; n = 217, 12-19 years; and n = 129, >20 years). Among adults, 39% were overweight/obese at last clinic visit; 22% overweight, and 17% obese. Childhood anthropometric data were available for 82 adults, of which 15% (n = 12/82) were overweight/obese in childhood. The likelihood of being overweight/obese as an adult was three times higher if there was a BMI ≥ 85th percentile in childhood (CI 2.1-4.5, P < 0.01). Overweight/obesity in adulthood was associated with lower heart failure rates (4 vs. 19%, P = 0.03). Pediatric rates of overweight/obesity were comparable to national data (NHANES 2011-2012) in every age group: at 2-5 years, (25 vs. 23%), 6-11 years (26 vs. 34%), and 12-19 years (15 vs. 35%). Systolic blood pressure was higher in overweight/obese children as young as 2-5 years of age. Childhood and adult survivors with Fontan circulation have high rates of overweight/obesity. Childhood obesity is a strong predictor of future adiposity and is linked to changes in systolic blood pressure at a very young age.

Indexed as

AdolescentAdultBody Mass IndexChildChild, PreschoolFontan ProcedureHumansLongitudinal StudiesMiddle AgedObesityOverweightPrevalenceRetrospective StudiesRisk FactorsYoung AdultCongenitalFontan procedureGrowthHeart defectObesityPediatrics

Identifiers

PMID26377100
PMCPMC6260821
OpenAlexW1671998852

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.