Evidence map›Paper›PMID 26376882›Full record

ArticleEuropean radiology2016

Comparison of the diagnostic performance of digital breast tomosynthesis and magnetic resonance imaging added to digital mammography in women with known breast cancers.

Won Hwa Kim, Jung Min Chang, Hyeong-Gon Moon, Ann Yi, Hye Ryoung Koo, Hye Mi Gweon, Woo Kyung Moon

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

  1. Occult breast cancer in an older woman: A case report.Experimental and therapeutic medicine · 2025
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  12. Consensus Meeting of Breast Imaging: BI-RADS® and Beyond.Breast care (Basel, Switzerland) · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Won Hwa KimDepartment of Radiology, Seoul National University Hospital, 101 Daehangno, Jongno-gu, Seoul, 110-744, Republic of Korea.
Jung Min ChangDepartment of Radiology, Seoul National University Hospital, 101 Daehangno, Jongno-gu, Seoul, 110-744, Republic of Korea. imchangjm@gmail.com.
Hyeong-Gon MoonDepartment of Surgery, Seoul National University Hospital, Seoul, Republic of Korea.
Ann YiDepartment of Radiology, Gangnan Healthcare Center, Seoul National University Hospital, Seoul, Korea.
Hye Ryoung KooDepartment of Radiology, Hanyang University College of Medicine, Seoul, Korea.
Hye Mi GweonDepartment of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Woo Kyung MoonDepartment of Radiology, Seoul National University Hospital, 101 Daehangno, Jongno-gu, Seoul, 110-744, Republic of Korea.
Seoul National University Hospital · KRGangnam Severance Hospital · KRHanyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the diagnostic performance of digital breast tomosynthesis (DBT) and magnetic resonance imaging (MRI) added to mammography in women with known breast cancers.

methodsThree radiologists independently reviewed image sets of 172 patients with 184 cancers; mammography alone, DBT plus mammography and MRI plus mammography, and scored for cancer probability using the Breast Imaging Reporting and Data System (BI-RADS). Jack-knife alternative free-response receiver-operating characteristic (JAFROC), which allows diagnostic performance estimation using single lesion as a statistical unit in a cancer-only population, was used. Sensitivity and positive predictive value (PPV) were compared using the McNemar and Fisher-exact tests.

resultsThe JAFROC figures of merit (FOMs) was lower in DBT plus mammography (0.937) than MRI plus mammography (0.978, P = 0.0006) but higher than mammography alone (0.900, P = 0 .0013). The sensitivity was lower in DBT plus mammography (88.2 %) than MRI plus mammography (97.8 %) but higher than mammography alone (78.3 %, both P < 0 .0001). The PPV was significantly higher in DBT plus mammography (93.3 %) than MRI plus mammography (89.6 %, P = 0 .0282).

conclusionsDBT provided lower diagnostic performance than MRI as an adjunctive imaging to mammography. However, DBT had higher diagnostic performance than mammography and higher PPV than MRI. KEY POINTS: • Digital breast tomosynthesis (DBT) plus mammography was compared with MRI plus mammography. • DBT had lower sensitivity and higher PPV than MRI. • DBT had higher diagnostic performance than mammography.

Indexed as

Adenocarcinoma, MucinousAdultAgedBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularFemaleHumansImaging, Three-DimensionalMagnetic Resonance ImagingMammographyMiddle AgedROC CurveSensitivity and SpecificityTumor BurdenBreast neoplasms/pathologyImagingMagnetic resonance imagingSensitivity and specificityThree-dimensional, mammography

Identifiers

PMID26376882
OpenAlexW1746249422

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.