Observational studyJournal of translational medicine2015
Nutritional parameters predicting pressure ulcers and short-term mortality in patients with minimal conscious state as a result of traumatic and non-traumatic acquired brain injury.
Observational study in Journal of translational medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
- Standardized operating room nursing care is effective in preventing the occurrence of surgical wound infections.American journal of translational research · 2025Article
- Clinical Presentation and Integrated Management of Pressure Injuries in the Emergency Hospital Setting: A Plastic Surgeon's Perspective.Healthcare (Basel, Switzerland) · 2024Article
- Prognostic Evaluation of Disorders of Consciousness by Using Resting-State fMRI: A Systematic Review.Journal of clinical medicine · 2024Review
- Procalcitonin/Albumin Ratio Predicts the Outcome After Severe Traumatic Brain Injury: A Propensity Score-Matched Analysis.Neurocritical care · 2024Article
- The clinical value of inflammation index in predicting ICU mortality of critically ill patients with intracerebral hemorrhage.Frontiers in public health · 2024Article
- Multidimensional-Based Prediction of Pressure Ulcers Development and Severity in Hospitalized FrailClinical interventions in aging · 2024Article
- Article
- C-reactive Protein/Albumin Ratio as a Prognostic Indicator in Posttraumatic Shock and Outcome of Multiple Trauma Patients.Current medical science · 2023Article
- Article
- C-reactive protein-albumin ratio and procalcitonin in predicting intensive care unit mortality in traumatic brain injury.Acute and critical care · 2022Article
- Lactate Albumin Ratio Is Associated With Mortality in Patients With Moderate to Severe Traumatic Brain Injury.Frontiers in neurology · 2022Article
- A prediction model of clinical outcomes in prolonged disorders of consciousness: A prospective cohort study.Frontiers in neuroscience · 2022Article
- A multi-domain prognostic model of disorder of consciousness using resting-state fMRI and laboratory parameters.Brain imaging and behavior · 2021Article
- Reactive Oxygen Species and Pressure Ulcer Formation after Traumatic Injury to Spinal Cord and Brain.Antioxidants (Basel, Switzerland) · 2021Review
- Selected Biochemical Blood Parameters and a Risk of Pressure Ulcers in Patients Receiving Treatment in Intensive Care Units.Medicina (Kaunas, Lithuania) · 2021Article
- The clinical effect of nursing intervention in the operating room on the prevention of orthopedic wound infections.American journal of translational research · 2021Article
- Role of Albumin as a Nutritional and Prognostic Marker in Elective Intestinal Surgery.Canadian journal of gastroenterology & hepatology · 2020Article
- Pressure Ulcer and Nutrition.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2018Review
- Traumatic brain injury and palliative care: a retrospective analysis of 49 patients receiving palliative care during 2013-2016 in Turkey.Neural regeneration research · 2017Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe association between malnutrition and worse outcomes as pressure ulcers and mortality is well established in a variety of setting. Currently none investigation was conducted in patients with long-term consequences of the acquired brain injury in which recovery from brain injury could be influenced by secondary complications. The aim of this study was to investigate the association between various nutritional status parameters (in particular albumin) and pressure ulcers formation and short-term mortality in minimal conscious state patients.
methodsIn this prospective, observational study of 5-months duration, a 30 patients sample admitted to a Neurological Institute was considered. All patients underwent a complete medical examination. Anthropometric parameters like mid-arm circumference and mid-arm muscle circumference and nutritional parameters as serum albumin and blood hemoglobin concentration were assessed.
resultsAt univariate and logistic regression analysis, mid-arm circumference (p = 0.04; beta = -0.89), mid-arm muscle circumference (p = 0.050; beta = -1.29), hemoglobin (p = 0.04, beta -1.1) and albumin (p = 0.04, beta -7.91) were inversely associated with pressure ulcers. The area under the ROC curve for albumin to predict sores was 0.76 (p = 0.02) and mortality was 0.83 (p = 0.03). Patient with lower albumin had significantly higher short-term mortality than those with higher serum albumin (p = 0.03; χ(2) test = 6.47).
conclusionAlbumin, haemoglobin and mid-arm circumference are inversely associated with pressure ulcers. Albumin is a prognostic index in MCS patients. Since albumin and haemoglobin could be affected by a variety of factors, this association suggests to optimize nutrition and investigate on other mechanism leading to mortality and pressure ulcers.
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