ArticleJournal of neuroinflammation2015
Acute hemorrhagic leukoencephalitis (Weston-Hurst syndrome) in a patient with relapse-remitting multiple sclerosis.
Article in Journal of neuroinflammation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Acute Hemorrhagic Leukoencephalitis: A Case and Systematic Review of the Literature.Frontiers in neurology · 2020Pooled it
- CASE REPORT: Fulminant acute hemorrhagic Leukoencephalitis (AHLE): A rare and ruinous outcome with cerebral herniation (COVID-19).eNeurologicalSci · 2024Article
- [Weston-Hurst syndrome. A case report and literature review].Revista medica del Instituto Mexicano del Seguro Social · 2023Review
- [Acute disseminated encephalomyelitis].Der Radiologe · 2022Review
- Acute Hemorrhagic Leukoencephalitis (AHLE): A Comprehensive Review on Causes, Symptoms, Link with COVID-19, Diagnosis, and Treatment.BioMed research international · 2022Review
- Case Report: Minimal Neurological Deficit of Two Adult Patients With Weston-Hurst Syndrome Due to Early Craniectomy: Case Series and Review of Literature on Craniectomy.Frontiers in neurology · 2021Article
- Acute Disseminated Encephalomyelitis.HCA healthcare journal of medicine · 2020Article
- Sudden Death of a Young Man by Acute Hemorrhagic Leukoencephalitis.Academic forensic pathology · 2017Article
- Weston-Hurst syndrome: a rare fulminant form of acute disseminated encephalomyelitis (ADEM).BMJ case reports · 2016Article
- Commentary: Acute Hemorrhagic Leukoencephalitis (Weston-Hurst Syndrome) in a Patient with Relapse-Remitting Multiple Sclerosis.Frontiers in immunology · 2016Article
- Favourable Outcome in a 33-Year-Old Female with Acute Haemorrhagic Leukoencephalitis.Case reports in neurologyArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute hemorrhagic leukoencephalitis is a fulminant demyelinating disease and commonly considered as a rare and severe variant of acute disseminated encephalomyelitis. Here, we report the clinical, magnetic resonance imaging, and brain biopsy findings of a 35-year-old female with relapsing-remitting multiple sclerosis, who developed acute hemorrhagic leukoencephalitis. Magnetic resonance imaging revealed symmetrical hemorrhagic lesions in the basal ganglia including the thalami. Disease progression was consistent with acute hemorrhagic leukoencephalitis with rapid deterioration of consciousness and seizures. Besides hemorrhage, infiltration of neutrophils was detected in brain biopsy.Acute hemorrhagic leukoencephalitis, also known as Weston-Hurst syndrome, is an excessive immunological response of unknown etiology. So far, an association with multiple sclerosis has not been reported. The present case raises the question, whether acute hemorrhagic leukoencephalitis is a specific hyperacute form of acute disseminated encephalomyelitis, a severe and unspecific form of an immune response in the central nervous system, or belongs to the spectrum of tumefactive multiple sclerosis.
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Registered trials
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