Trial reportPloS one2015
A 12-Week Exercise Program for Pregnant Women with Obesity to Improve Physical Activity Levels: An Open Randomised Preliminary Study.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 40 papers, 17 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Fitness Improvement in Obese, Pregnant Women: an Intervention Trial (InterGOFIT)
Evaluation of the Effect of Live Streaming Exercise on the Improvement of Hepatic Steatosis and Fibrosis in Pregnant Women with MASLD and Its Study Based on the Liver-gut Axis Mechanism.
Who cites it
40 citing papers in PubMed, 17 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- Effects of lifestyle interventions in pregnancy on gestational diabetes: individual participant data and network meta-analysis.BMJ (Clinical research ed.) · 2026Pooled it
- Influence of Prenatal Exercise on Apgar Score and Health-Related Physical Fitness in Childhood: A Systematic Review and Meta-Analysis.Journal of pregnancy · 2026Pooled it
- Antenatal Physical Activity Interventions and Pregnancy Outcomes: A Systematic Review and Meta-Analysis With a Focus on Trial Quality.BJOG : an international journal of obstetrics and gynaecology · 2025Pooled it
- Systematic review of interventions in early pregnancy among pregnant individuals at risk for hyperglycemia.American journal of obstetrics & gynecology MFM · 2025Pooled it
- Comprehensive management of gestational diabetes mellitus: practical efficacy of exercise therapy and sustained intervention strategies.Frontiers in endocrinology · 2024Pooled it
- Key Components of Antenatal Lifestyle Interventions to Optimize Gestational Weight Gain: Secondary Analysis of a Systematic Review.JAMA network open · 2023Pooled it
- Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders: An umbrella review of randomised controlled trials and an updated meta-analysis.BJOG : an international journal of obstetrics and gynaecology · 2023Pooled it
- Implementation of Antenatal Lifestyle Interventions Into Routine Care: Secondary Analysis of a Systematic Review.JAMA network open · 2022Pooled it
- Physical Activity during Pregnancy and Newborn Body Composition: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Effect of prenatal aerobic exercises on maternal and neonatal outcomes: A systematic review and meta-analysis.Nursing open · 2021Pooled it
- Physical Exercise vs. Metformin to Improve Delivery- and Newborn-Related Outcomes Among Pregnant Women With Overweight: A Network Meta-Analysis.Frontiers in medicine · 2021Pooled it
- The effects of vigorous intensity exercise in the third trimester of pregnancy: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2019Pooled it
- Effectiveness of Physical Activity Interventions on Pregnancy-Related Outcomes among Pregnant Women: A Systematic Review.International journal of environmental research and public health · 2019Pooled it
- Attenuating Pregnancy Weight Gain-What Works and Why: A Systematic Review and Meta-Analysis.Nutrients · 2018Pooled it
- Antepartum Care of Women Who Are Obese During Pregnancy: Systematic Review of the Current Evidence.Journal of midwifery & women's health · 2018Pooled it
- Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: meta-analysis of individual participant data from randomised trials.BMJ (Clinical research ed.) · 2017Pooled it
- Interventions to increase self-reported physical activity during pregnancy: A systematic review.Women's health (London, England)Pooled it
- Development and feasibility of a theory-guided and evidence-based physical activity intervention in pregnant women with high risk for gestational diabetes mellitus: a pilot clinical trial.BMC pregnancy and childbirth · 2023Trial
- Effects of Two Physical Activity Interventions on Sleep and Sedentary Time in Pregnant Women.International journal of environmental research and public health · 2023Trial
- Examination of influence of social media education through mobile phones on the change in physical activity and sedentary behavior in pregnant women: a randomized controlled trial.BMC women's health · 2022Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate whether a 12-week supervised exercise program promotes an active lifestyle throughout pregnancy in pregnant women with obesity.
methodsIn this preliminary randomised trial, pregnant women (body mass index ≥ 30 kg/m2) were allocated to either standard care or supervised training, from 15 to 27 weeks of gestation. Physical activity was measured by accelerometry at 14, 28 and 36 weeks, while fitness (oxygen consumption (VO2) at the anaerobic threshold), nutrition (caloric intake and macronutrients percentage) and anthropometry were assessed at 14 and 28 weeks of gestation. Analyses were performed using repeated measures ANOVA.
resultsA total of fifty (50) women were randomised, 25 in each group. There was no time-group interaction for time spent at moderate and vigorous activity (pinteraction = 0.064), but the exercise group's levels were higher than controls' at all times (pgroup effect = 0.014). A significant time-group interaction was found for daily physical activity (p = 0.023); similar at baseline ((22.0 ± 6.7 vs 21.8 ± 7.3) x 10(4) counts/day) the exercise group had higher levels than the control group following the intervention ((22.8 ± 8.3 vs 19.2 ± 4.5) x 10(4) counts/day, p = 0.020) and at 36 weeks of gestation ((19.2 ± 1.5 vs 14.9 ± 1.5) x 10(4) counts/day, p = 0.034). Exercisers also gained less weight than controls during the intervention period despite similar nutritional intakes (difference in weight change = -0.1 kg/week, 95% CI -0.2; -0.02, p = 0.016) and improved cardiorespiratory fitness (difference in fitness change = 8.1%, 95% CI 0.7; 9.5, p = 0.041).
conclusionsCompared with standard care, a supervised exercise program allows pregnant women with obesity to maintain fitness, limit weight gain and attenuate the decrease in physical activity levels observed in late pregnancy.
trial registrationClinicalTrials.gov NCT01610323.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.