Evidence map›Paper›PMID 26374614›Full record

ArticleBMJ (Clinical research ed.)2015

Potential of trans fats policies to reduce socioeconomic inequalities in mortality from coronary heart disease in England: cost effectiveness modelling study.

Kirk Allen, Jonathan Pearson-Stuttard, William Hooton, Peter Diggle, Simon Capewell, Martin O'Flaherty

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. A Systematic Review of Economic Evaluations of Health-Promoting Food Retail-Based Interventions.International journal of environmental research and public health · 2021
    Pooled it
  3. Systematic review of dietary trans-fat reduction interventions.Bulletin of the World Health Organization · 2017
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  7. Costa Rica's trans-fat ban impact on cardiovascular disease: a macrosimulation study.Revista panamericana de salud publica = Pan American journal of public health · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Kirk AllenLancaster Medical School, Lancaster University, Lancaster LA1 4YW, UK Department of Public Health and Policy, Liverpool University, Liverpool L69 3GB, UK allenk@liverpool.ac.uk.
Jonathan Pearson-StuttardDivision of Medical Sciences, University of Oxford, Oxford OX3 9DU, UK.
William HootonPembroke College Alumni, University of Oxford, Oxford OX1 1DW, UK.
Peter DiggleLancaster Medical School, Lancaster University, Lancaster LA1 4YW, UK.
Simon CapewellDepartment of Public Health and Policy, Liverpool University, Liverpool L69 3GB, UK.
Martin O'FlahertyDepartment of Public Health and Policy, Liverpool University, Liverpool L69 3GB, UK.

Funding

Medical Research Council G0900847
6 · The paper itself

Abstract

objectivesTo determine health and equity benefits and cost effectiveness of policies to reduce or eliminate trans fatty acids from processed foods, compared with consumption remaining at most recent levels in England.

designEpidemiological modelling study.

settingData from National Diet and Nutrition Survey, Low Income Diet and Nutrition Survey, Office of National Statistics, and health economic data from other published studies

participantsAdults aged ≥25, stratified by fifths of socioeconomic circumstance.

interventionsTotal ban on trans fatty acids in processed foods; improved labelling of trans fatty acids; bans on trans fatty acids in restaurants and takeaways.

main outcome measuresDeaths from coronary heart disease prevented or postponed; life years gained; quality adjusted life years gained. Policy costs to government and industry; policy savings from reductions in direct healthcare, informal care, and productivity loss.

resultsA total ban on trans fatty acids in processed foods might prevent or postpone about 7200 deaths (2.6%) from coronary heart disease from 2015-20 and reduce inequality in mortality from coronary heart disease by about 3000 deaths (15%). Policies to improve labelling or simply remove trans fatty acids from restaurants/fast food could save between 1800 (0.7%) and 3500 (1.3%) deaths from coronary heart disease and reduce inequalities by 600 (3%) to 1500 (7%) deaths, thus making them at best half as effective. A total ban would have the greatest net cost savings of about £265m (€361m, $415m) excluding reformulation costs, or £64m if substantial reformulation costs are incurred outside the normal cycle.

conclusionsA regulatory policy to eliminate trans fatty acids from processed foods in England would be the most effective and equitable policy option. Intermediate policies would also be beneficial. Simply continuing to rely on industry to voluntary reformulate products, however, could have negative health and economic outcomes.

Indexed as

AdultCoronary DiseaseCost-Benefit AnalysisCost SavingsEnglandFood HandlingHumansLegislation, FoodQuality-Adjusted Life YearsSocioeconomic FactorsTrans Fatty AcidsTrans Fatty Acids

Identifiers

PMID26374614
PMCPMC4569940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.