ArticleBMJ (Clinical research ed.)2015
Potential of trans fats policies to reduce socioeconomic inequalities in mortality from coronary heart disease in England: cost effectiveness modelling study.
Article in BMJ (Clinical research ed.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Incorporating Equity Concerns in Cost-Effectiveness Analyses: A Systematic Literature Review.PharmacoEconomics · 2022Pooled it
- A Systematic Review of Economic Evaluations of Health-Promoting Food Retail-Based Interventions.International journal of environmental research and public health · 2021Pooled it
- Systematic review of dietary trans-fat reduction interventions.Bulletin of the World Health Organization · 2017Pooled it
- Impact of diets high in trans-fatty acids on cardiovascular diseases in adults aged 55 and older: insights from the Global Burden of Disease 2021 data.Frontiers in nutrition · 2026Article
- Disparities Research in Pediatric Orthopaedic Surgery: Is the Needle Moving?Journal of pediatric orthopedics · 2025Article
- Trans-Fatty Acids (TFA) Induced Vascular Injury Through the Regulation of the Sirt1-Ppargc1a-Nfe2l2 Signaling Pathway in Male Rats.Food science & nutrition · 2025Article
- Costa Rica's trans-fat ban impact on cardiovascular disease: a macrosimulation study.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- Estimated health benefits, costs and cost-effectiveness of eliminating industrial transBMJ global health · 2024Article
- Distinct gut flora profile induced by postnatal trans-fat diet in gestationally bisphenol A-exposed rats.PloS one · 2024Article
- Projecting cardiovascular deaths averted due to trans fat policies in the Eurasian Economic Union.Public health nutrition · 2023Article
- Estimated health benefits, costs and cost-effectiveness of eliminating dietary industrial trans fatty acids in Kenya: cost-effectiveness analysis.BMJ global health · 2023Article
- Modelled Distributional Cost-Effectiveness Analysis of Childhood Obesity Interventions: A Demonstration.Applied health economics and health policy · 2023Article
- The effects of trans fat diet intake on metabolic parameters and pancreatic tissue in offspring of prenatal bisphenol A exposed rats.Scientific reports · 2023Article
- Development and application of the TFA macrosimulation model: a case study of modelling the impact of trans fatty acid (TFA) elimination policies in Brazil.BMC public health · 2022Article
- Article
- Simulation Modeling for the Economic Evaluation of Population-Based Dietary Policies: A Systematic Scoping Review.Advances in nutrition (Bethesda, Md.) · 2021Article
- Framework for the development and evaluation of complex interventions: gap analysis, workshop and consultation-informed update.Health technology assessment (Winchester, England) · 2021Article
- Trans Fat Free by 2023-A Building Block of the COVID-19 Response.Frontiers in nutrition · 2021Article
- Estimated health benefits, costs, and cost-effectiveness of eliminating industrial trans-fatty acids in Australia: A modelling study.PLoS medicine · 2020Article
- Potential impacts of post-Brexit agricultural policy on fruit and vegetable intake and cardiovascular disease in England: a modelling study.BMJ nutrition, prevention & health · 2020Article
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Authors and funding
6 authors.
Funding
Abstract
objectivesTo determine health and equity benefits and cost effectiveness of policies to reduce or eliminate trans fatty acids from processed foods, compared with consumption remaining at most recent levels in England.
designEpidemiological modelling study.
settingData from National Diet and Nutrition Survey, Low Income Diet and Nutrition Survey, Office of National Statistics, and health economic data from other published studies
participantsAdults aged ≥25, stratified by fifths of socioeconomic circumstance.
interventionsTotal ban on trans fatty acids in processed foods; improved labelling of trans fatty acids; bans on trans fatty acids in restaurants and takeaways.
main outcome measuresDeaths from coronary heart disease prevented or postponed; life years gained; quality adjusted life years gained. Policy costs to government and industry; policy savings from reductions in direct healthcare, informal care, and productivity loss.
resultsA total ban on trans fatty acids in processed foods might prevent or postpone about 7200 deaths (2.6%) from coronary heart disease from 2015-20 and reduce inequality in mortality from coronary heart disease by about 3000 deaths (15%). Policies to improve labelling or simply remove trans fatty acids from restaurants/fast food could save between 1800 (0.7%) and 3500 (1.3%) deaths from coronary heart disease and reduce inequalities by 600 (3%) to 1500 (7%) deaths, thus making them at best half as effective. A total ban would have the greatest net cost savings of about £265m (€361m, $415m) excluding reformulation costs, or £64m if substantial reformulation costs are incurred outside the normal cycle.
conclusionsA regulatory policy to eliminate trans fatty acids from processed foods in England would be the most effective and equitable policy option. Intermediate policies would also be beneficial. Simply continuing to rely on industry to voluntary reformulate products, however, could have negative health and economic outcomes.
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