ReviewCurrent diabetes reports2015
Diabetes-related dysfunction of the small intestine and the colon: focus on motility.
Review in Current diabetes reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06340217 (The Efficacy and Safety of WMT in the Treatment of Diabetic Gastroparesis), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Efficacy and Safety of WMT in the Treatment of Diabetic Gastroparesis: A Multicenter, Randomized, Double-blind, Placebo-controlled Study
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Acute colonic pseudo-obstruction: A systematic review of aetiology and mechanisms.World journal of gastroenterology · 2017Pooled it
- Effects of prucalopride succinate on postoperative bowel motility and inflammation following minimally invasive gastrectomy.Scientific reports · 2026Trial
- Repeated faecal microbiota transplantation for individuals with type 1 diabetes and gastroenteropathy.Diabetologia · 2025Trial
- A randomized controlled study to assess the effect of mosapride citrate on intestinal recovery following gastrectomy.Scientific reports · 2024Trial
- Diabetic gastroenteropathy: Associations between gastrointestinal symptoms, motility, and extraintestinal autonomic measures.Neurogastroenterology and motility · 2026Article
- Diabetic gastroenteropathy: a pan-alimentary complication.Diabetologia · 2025Review
- Panenteric Transit Times and Contractile Activity in Diabetic Gastroenteropathy.Journal of neurogastroenterology and motility · 2025Article
- Association of constipation with all-cause mortality among individuals with type 2 diabetes: A retrospective cohort study.Journal of diabetes investigation · 2025Article
- Oxidative Stress and Histomorphometric Remodeling: Two Key Intestinal Features of Type 2 Diabetes in Goto-Kakizaki Rats.International journal of molecular sciences · 2024Article
- Type 2 diabetes mellitus and post-colonoscopy colorectal cancer: clinical and molecular characteristics and survival.Cancer causes & control : CCC · 2024Article
- Enteric neuropathy in diabetes: Implications for gastrointestinal function.World journal of gastroenterology · 2024Article
- MRI-Based Quantification of Pan-Alimentary Function and Motility in Subjects with Diabetes and Gastrointestinal Symptoms.Journal of clinical medicine · 2023Article
- Impact of glucagon-like peptide 1 receptor agonist liraglutide and dipeptidyl peptidase-4 inhibitor sitagliptin on bowel cleaning and gastrointestinal symptoms in type 2 diabetes.Frontiers in pharmacology · 2023Article
- Histomorphometry Changes and Decreased Reactivity to Angiotensin II in the Ileum and Colon of Streptozotocin-Induced Diabetic Rats.International journal of molecular sciences · 2022Article
- Protease-activated receptor-mediated platelet aggregation in patients with type 2 diabetes on potent P2YDiabetic medicine : a journal of the British Diabetic Association · 2022Article
- Risk of a post-colonoscopy colorectal cancer in patients with type 2 diabetes: a Danish population-based cohort study.BMJ open gastroenterology · 2021Article
- Diabetic autonomic neuropathy of the gastrointestinal tract.Przeglad gastroenterologiczny · 2020Review
- Cardiovascular Autonomic Neuropathy and Glucose Variability in Patients With Type 1 Diabetes: Is There an Association?Frontiers in endocrinology · 2018Article
- Epigenetic modification of TLE1 induce abnormal differentiation in diabetic mice intestinal epithelium.Molecular and cellular biochemistry · 2018Article
- Diabetes Mellitus and the Colon.Current treatment options in gastroenterology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In contrast to gastric dysfunction, diabetes-related functional impairments of the small and large intestine have been studied less intensively. The gastrointestinal tract accomplishes several functions, such as mixing and propulsion of luminal content, absorption and secretion of ions, water, and nutrients, defense against pathogens, and elimination of waste products. Diverse functions of the gut are regulated by complex interactions among its functional elements, including gut microbiota. The network-forming tissues, the enteric nervous system) and the interstitial cells of Cajal, are definitely impaired in diabetic patients, and their loss of function is closely related to the symptoms in diabetes, but changes of other elements could also play a role in the development of diabetes mellitus-related motility disorders. The development of our understanding over the recent years of the diabetes-induced dysfunctions in the small and large intestine are reviewed in this article.
Indexed as
Identifiers
26374571What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.