Trial reportAnnals of biomedical engineering2016
A Patient-Specific Foot Model for the Estimate of Ankle Joint Forces in Patients with Juvenile Idiopathic Arthritis.
Trial report in Annals of biomedical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Subject-specific muscle properties from diffusion tensor imaging significantly improve the accuracy of musculoskeletal models.Journal of anatomy · 2020Trial
- Chronic Ankle Instability-Related Outcomes Associate With Ankle-Joint Loading During Walking.Journal of athletic training · 2025Article
- Development and validation of a novel ankle joint musculoskeletal model.Medical & biological engineering & computing · 2024Article
- Quantifying walking speeds in relation to ankle biomechanics on a real-time interactive gait platform: a musculoskeletal modeling approach in healthy adults.Frontiers in bioengineering and biotechnology · 2024Article
- The influence of induced gait asymmetry on joint reaction forces.Journal of biomechanics · 2023Article
- Predictions of Anterior Cruciate Ligament Dynamics From Subject-Specific Musculoskeletal Models and Dynamic Biplane Radiography.Journal of biomechanical engineering · 2021Article
- Biomechanical evaluation of total ankle arthroplasty. Part I: Joint loads during simulated level walking.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021Article
- Development and validation of statistical shape models of the primary functional bone segments of the foot.PeerJ · 2020Article
- Improving Musculoskeletal Model Scaling Using an Anatomical Atlas: The Importance of Gender and Anthropometric Similarity to Quantify Joint Reaction Forces.IEEE transactions on bio-medical engineering · 2019Article
- Linking Joint Impairment and Gait Biomechanics in Patients with Juvenile Idiopathic Arthritis.Annals of biomedical engineering · 2019Article
- In vivo human lower limb muscle architecture dataset obtained using diffusion tensor imaging.PloS one · 2019Article
- Relative movement on the articular surfaces of the tibiotalar and subtalar joints during walking.Bone & joint research · 2018Article
- Imaging in juvenile idiopathic arthritis - international initiatives and ongoing work.Pediatric radiology · 2018Review
- Sensitivity of a juvenile subject-specific musculoskeletal model of the ankle joint to the variability of operator-dependent input.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2017Article
- The influence of muscle pennation angle and cross-sectional area on contact forces in the ankle joint.The Journal of strain analysis for engineering design · 2017Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Juvenile idiopathic arthritis (JIA) is the leading cause of childhood disability from a musculoskeletal disorder. It generally affects large joints such as the knee and the ankle, often causing structural damage. Different factors contribute to the damage onset, including altered joint loading and other mechanical factors, associated with pain and inflammation. The prediction of patients' joint loading can hence be a valuable tool in understanding the disease mechanisms involved in structural damage progression. A number of lower-limb musculoskeletal models have been proposed to analyse the hip and knee joints, but juvenile models of the foot are still lacking. This paper presents a modelling pipeline that allows the creation of juvenile patient-specific models starting from lower limb kinematics and foot and ankle MRI data. This pipeline has been applied to data from three children with JIA and the importance of patient-specific parameters and modelling assumptions has been tested in a sensitivity analysis focused on the variation of the joint reaction forces. This analysis highlighted the criticality of patient-specific definition of the ankle joint axes and location of the Achilles tendon insertions. Patient-specific detection of the Tibialis Anterior, Tibialis Posterior, and Peroneus Longus origins and insertions were also shown to be important.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.