Evidence map›Paper›PMID 26374182›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2015

Intravenous Lipid Emulsions in Parenteral Nutrition.

Gillian L Fell, Prathima Nandivada, Kathleen M Gura, Mark Puder

Open access · bronzeAbstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  11. Heterogeneity of Biofilm Formation AmongAntibiotics (Basel, Switzerland) · 2025
    Article
  12. Essential fatty acid deficiency in parenteral nutrition: Historical perspective and modern solutions, a narrative review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Review
  13. Article
  14. Review
  15. Fat malabsorption in short bowel syndrome: A review of pathophysiology and management.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2024
    Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gillian L FellVascular Biology Program and Departments of Surgery and.
Prathima NandivadaVascular Biology Program and Departments of Surgery and.
Kathleen M GuraPharmacy, Boston Children's Hospital, Boston, MA.
Mark PuderVascular Biology Program and Departments of Surgery and mark.puder@childrens.harvard.edu.
Center for Vascular Biology Research · USBoston Children's Museum · US

Funding

Generation and use of lipid emulsions to understand mechanisms of and optimally manage parenteral nutrition associated liver diseaseF32DK104525 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI FELL, GILLIAN LYNAPP · 2014 to 2016
$163k
NIDDK NIH HHS 1F32DK104525-01
6 · The paper itself

Abstract

Fat is an important macronutrient in the human diet. For patients with intestinal failure who are unable to absorb nutrients via the enteral route, intravenous lipid emulsions play a critical role in providing an energy-dense source of calories and supplying the essential fatty acids that cannot be endogenously synthesized. Over the last 50 y, lipid emulsions have been an important component of parenteral nutrition (PN), and over the last 10-15 y many new lipid emulsions have been manufactured with the goal of improving safety and efficacy profiles and achieving physiologically optimal formulations. The purpose of this review is to provide a background on the components of lipid emulsions, their role in PN, and to discuss the lipid emulsions available for intravenous use. Finally, the role of parenteral fat emulsions in the pathogenesis and management of PN-associated liver disease in PN-dependent pediatric patients is reviewed.

Indexed as

Coconut OilFat Emulsions, IntravenousFish OilsHumansLiver DiseasesOlive OilParenteral Nutrition SolutionsPlant OilsSafflower OilSoybean OilCoconut OilFat Emulsions, IntravenousFish OilsOlive OilParenteral Nutrition SolutionsPlant OilsSafflower OilSoybean Oilfatty acidslipid metabolismparenteral nutritionparenteral nutrition-associated liver diseaseω-3 fatty acids

Identifiers

PMID26374182
PMCPMC4561835
OpenAlexW2176132997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.