ArticleProceedings of the National Academy of Sciences of the United States of America2015
Suburbanization, estrogen contamination, and sex ratio in wild amphibian populations.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 109 citations in OpenAlex.
- Article
- Variations in Sexual Size Dimorphism in Two Anurans Along an Urbanization Gradient in Shanghai: Assessment of Rensch's Rule.Ecology and evolution · 2026Article
- A native bacterial consortium degrades estriol in domestic sewage and activated sludge via the 4,5-Microbiology spectrum · 2025Article
- Bacterial estrogenesis without oxygen: Wood-Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Diversity of estrogen biodegradation pathways and application in environmental bioremediation.Frontiers in microbiology · 2025Review
- Exploring ethylene-related genes in Cannabis sativa: implications for sexual plasticity.Plant reproduction · 2024Article
- Framework for multi-stressor physiological response evaluation in amphibian risk assessment and conservation.Frontiers in ecology and evolution · 2024Article
- Big boned: How fat storage and other adaptations influenced large theropod foraging ecology.PloS one · 2023Article
- Isolation of Environmental Bacteria Able to Degrade Sterols and/or Bile Acids: Determination of Cholesterol Oxidase and Several Hydroxysteroid Dehydrogenase Activities in Rhodococcus, Gordonia, and Pseudomonas putida.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Impact of Estrogens Present in Environment on Health and Welfare of Animals.Animals : an open access journal from MDPI · 2021Review
- Modeling estrogenic activity in streams throughout the Potomac and Chesapeake Bay watersheds.Environmental monitoring and assessment · 2021Article
- Monitoring wetland water quality related to livestock grazing in amphibian habitats.Environmental monitoring and assessment · 2021Article
- Microplastic ingestion by tadpoles of pond-breeding amphibians-first results from Central Europe (SW Poland).Environmental science and pollution research international · 2020Article
- Microbial degradation of steroid sex hormones: implications for environmental and ecological studies.Microbial biotechnology · 2020Review
- Reconnaissance of Surface Water Estrogenicity and the Prevalence of Intersex in Smallmouth Bass (International journal of environmental research and public health · 2020Article
- Retroconversion of estrogens into androgens by bacteria via a cobalamin-mediated methylation.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Exposure to Artificial Light at Night and the Consequences for Flora, Fauna, and Ecosystems.Frontiers in neuroscience · 2020Review
- Article
- Occurrence, sorption, and transformation of free and conjugated natural steroid estrogens in the environment.Environmental science and pollution research international · 2019Review
- Metabolites Involved in Aerobic Degradation of the A and B Rings of Estrogen.Applied and environmental microbiology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research on endocrine disruption in frog populations, such as shifts in sex ratios and feminization of males, has predominantly focused on agricultural pesticides. Recent evidence suggests that suburban landscapes harbor amphibian populations exhibiting similar levels of endocrine disruption; however the endocrine disrupting chemical (EDC) sources are unknown. Here, we show that sex ratios of metamorphosing frogs become increasingly female-dominated along a suburbanization gradient. We further show that suburban ponds are frequently contaminated by the classical estrogen estrone and a variety of EDCs produced by plants (phytoestrogens), and that the diversity of organic EDCs is correlated with the extent of developed land use and cultivated lawn and gardens around a pond. Our work also raises the possibility that trace-element contamination associated with human land use around suburban ponds may be contributing to the estrogenic load within suburban freshwaters and constitutes another source of estrogenic exposure for wildlife. These data suggest novel, unexplored pathways of EDC contamination in human-altered environments. In particular, we propose that vegetation changes associated with suburban neighborhoods (e.g., from forests to lawns and ornamental plants) increase the distribution of phytoestrogens in surface waters. The result of frog sex ratios varying as a function of human land use implicates a role for environmental modulation of sexual differentiation in amphibians, which are assumed to only have genetic sex determination. Overall, we show that endocrine disruption is widespread in suburban frog populations and that the causes are likely diverse.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.