ArticlePLoS neglected tropical diseases2015
Syndromic Approach to Arboviral Diagnostics for Global Travelers as a Basis for Infectious Disease Surveillance.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- The increasing complexity of arbovirus serology: An in-depth systematic review on cross-reactivity.PLoS neglected tropical diseases · 2023Pooled it
- Chikungunya: risks for travellers.Journal of travel medicine · 2023Review
- Clinical Diagnosis of Chikungunya Infection: An Essential Aid in a Primary Care Setting Where Serological Confirmation Is Not Available.Tropical medicine and infectious disease · 2023Article
- Screening of febrile patients with suspected malaria from the Brazilian Amazon for virus infection.Archives of virology · 2022Article
- Rift Valley Fever: Important Considerations for Risk Mitigation and Future Outbreaks.Tropical medicine and infectious disease · 2020Review
- Importation of dengue, Zika and chikungunya infections in Europe: the current situation in Greece.New microbes and new infections · 2020Review
- Neighborhood Violence Impacts Disease Control and Surveillance: Case Study of Cali, Colombia from 2014 to 2016.International journal of environmental research and public health · 2018Article
- Review
- Mosquito Exposure and Chikungunya and Dengue Infection Among Travelers During the Chikungunya Outbreak in the Americas.The American journal of tropical medicine and hygiene · 2017Article
- A diagnostic and epidemiologic investigation of acute febrile illness (AFI) in Kilombero, Tanzania.PloS one · 2017Article
- Clinical evaluation of a single-reaction real-time RT-PCR for pan-dengue and chikungunya virus detection.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArboviruses have overlapping geographical distributions and can cause symptoms that coincide with more common infections. Therefore, arbovirus infections are often neglected by travel diagnostics. Here, we assessed the potential of syndrome-based approaches for diagnosis and surveillance of neglected arboviral diseases in returning travelers.
methodTo map the patients high at risk of missed clinical arboviral infections we compared the quantity of all arboviral diagnostic requests by physicians in the Netherlands, from 2009 through 2013, with a literature-based assessment of the travelers' likely exposure to an arbovirus.
results2153 patients, with travel and clinical history were evaluated. The diagnostic assay for dengue virus (DENV) was the most commonly requested (86%). Of travelers returning from Southeast Asia with symptoms compatible with chikungunya virus (CHIKV), only 55% were tested. For travelers in Europe, arbovirus diagnostics were rarely requested. Over all, diagnostics for most arboviruses were requested only on severe clinical presentation.
conclusionTravel destination and syndrome were used inconsistently for triage of diagnostics, likely resulting in vast under-diagnosis of arboviral infections of public health significance. This study shows the need for more awareness among physicians and standardization of syndromic diagnostic algorithms.
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