ArticleProceedings of the National Academy of Sciences of the United States of America2015
MYB36 regulates the transition from proliferation to differentiation in the Arabidopsis root.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
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Who cites it
82 citing papers in PubMed, 192 citations in OpenAlex.
- The GAPLESS-OsCASP complex mediates Casparian strip formation for proper localization and abundance of endodermal proteins in rice.Science advances · 2026Article
- Regulatory Roles of MYB Transcription Factors in Root Barrier Under Abiotic Stress.Plants (Basel, Switzerland) · 2026Review
- Dual roles of suberin deposition at the endodermal Casparian strip in manganese uptake of rice.Journal of experimental botany · 2025Article
- Integrated single-cell transcriptomics and spatial metabolomics unveil cellular differentiation and ginsenosides biosynthesis inHorticulture research · 2025Article
- Coordination of cortex modifications in time, space, and under stress.The New phytologist · 2025Review
- Transcriptional regulation of thorn tip sclerification in plants.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Cell-Type Specific miRNA Regulatory Network Responses to ABA Stress Revealed by Time Series Transcriptional Atlases in Arabidopsis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Heat waves reveal additive genetic effects leading to sunburn resilience of grapevine berries.Frontiers in plant science · 2025Article
- Regulation and function of a polarly localized lignin barrier in the exodermis.Nature plants · 2025Article
- Research on the function ofPlant signaling & behavior · 2024Article
- Rooting for survival: how plants tackle a challenging environment through a diversity of root forms and functions.Plant physiology · 2024Review
- Four MYB transcription factors regulate suberization and nonlocalized lignification at the root endodermis in rice.The Plant cell · 2024Article
- Root apoplastic barrier mechanism: an adaptive strategy to protect against salt stress.Molecular biology reports · 2024Review
- Exploring the function of plant root diffusion barriers in sealing and shielding for environmental adaptation.Nature plants · 2024Review
- Comparative Analysis of Casparian Strip Membrane Domain Protein Family inInternational journal of molecular sciences · 2024Article
- Comparisons of two receptor-MAPK pathways in a single cell-type reveal mechanisms of signalling specificity.Nature plants · 2024Article
- Single-cell network analysis reveals gene expression programs for Arabidopsis root development and metabolism.Plant communications · 2024Article
- The Arabidopsis SGN3/GSO1 receptor kinase integrates soil nitrogen status into shoot development.The EMBO journal · 2024Article
- Light controls mesophyll-specific post-transcriptional splicing of photoregulatory genes by AtPRMT5.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
22 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Stem cells are defined by their ability to self-renew and produce daughter cells that proliferate and mature. These maturing cells transition from a proliferative state to a terminal state through the process of differentiation. In the Arabidopsis thaliana root the transcription factors SCARECROW and SHORTROOT regulate specification of the bipotent stem cell that gives rise to cortical and endodermal progenitors. Subsequent progenitor proliferation and differentiation generate mature endodermis, marked by the Casparian strip, a cell-wall modification that prevents ion diffusion into and out of the vasculature. We identified a transcription factor, MYB DOMAIN PROTEIN 36 (MYB36), that regulates the transition from proliferation to differentiation in the endodermis. We show that SCARECROW directly activates MYB36 expression, and that MYB36 likely acts in a feed-forward loop to regulate essential Casparian strip formation genes. We show that myb36 mutants have delayed and defective barrier formation as well as extra divisions in the meristem. Our results demonstrate that MYB36 is a critical positive regulator of differentiation and negative regulator of cell proliferation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.