ArticlePlant physiology2015
Integrative Approaches to Enhance Understanding of Plant Metabolic Pathway Structure and Regulation.
Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Mechanisms and precision interventions in sarcopenia and osteoarthritis comorbidity: A narrative review.Journal of orthopaedic translation · 2026Review
- Fertilizer placement modulates the effects of soil metabolite formulations on nutrient status, phenylpropanoid-flavonoid metabolism, and sensory quality in flue-cured tobacco.Frontiers in plant science · 2026Article
- Integrated analysis of metabolites and enzyme activities reveals the plasticity of central carbon metabolism in grape (Horticulture research · 2025Article
- The natural variance of Arabidopsis secondary metabolism on extended darkness.Scientific data · 2024Article
- Using precision phenotyping to inform de novo domestication.Plant physiology · 2021Article
- The Contribution of Metabolomics to Systems Biology: Current Applications Bridging Genotype and Phenotype in Plant Science.Advances in experimental medicine and biology · 2021Article
- Identification and characterization of metabolite quantitative trait loci in tomato leaves and comparison with those reported for fruits and seeds.Metabolomics : Official journal of the Metabolomic Society · 2019Article
- Computational Approaches to Design and Test Plant Synthetic Metabolic Pathways.Plant physiology · 2019Review
- Crop metabolomics: from diagnostics to assisted breeding.Metabolomics : Official journal of the Metabolomic Society · 2018Review
- Putting primary metabolism into perspective to obtain better fruits.Annals of botany · 2018Review
- The natural variance of the Arabidopsis floral secondary metabolites.Scientific data · 2018Article
- Combined Drought and Heat Activates Protective Responses inFrontiers in plant science · 2018Article
- Data Reduction Approaches for Dissecting Transcriptional Effects on Metabolism.Frontiers in plant science · 2018Article
- Relationships between drought, heat and air humidity responses revealed by transcriptome-metabolome co-analysis.BMC plant biology · 2017Article
- From chromatogram to analyte to metabolite. How to pick horses for courses from the massive web resources for mass spectral plant metabolomics.GigaScience · 2017Review
- Integrated genomics-based mapping reveals the genetics underlying maize flavonoid biosynthesis.BMC plant biology · 2017Article
- Genome-metabolite associations revealed low heritability, high genetic complexity, and causal relations for leaf metabolites in winter wheat (Triticum aestivum).Journal of experimental botany · 2017Article
- Characterization of a recently evolved flavonol-phenylacyltransferase gene provides signatures of natural light selection in Brassicaceae.Nature communications · 2016Article
- Focus Issue on Metabolism: Metabolites, Metabolites Everywhere.Plant physiology · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Huge insight into molecular mechanisms and biological network coordination have been achieved following the application of various profiling technologies. Our knowledge of how the different molecular entities of the cell interact with one another suggests that, nevertheless, integration of data from different techniques could drive a more comprehensive understanding of the data emanating from different techniques. Here, we provide an overview of how such data integration is being used to aid the understanding of metabolic pathway structure and regulation. We choose to focus on the pairwise integration of large-scale metabolite data with that of the transcriptomic, proteomics, whole-genome sequence, growth- and yield-associated phenotypes, and archival functional genomic data sets. In doing so, we attempt to provide an update on approaches that integrate data obtained at different levels to reach a better understanding of either single gene function or metabolic pathway structure and regulation within the context of a broader biological process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.