ReviewAge (Dordrecht, Netherlands)2015
Improving healthspan via changes in gut microbiota and fermentation.
Review in Age (Dordrecht, Netherlands), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
- Exploring the Link Between the Gut Microbiota and Epigenetic Factors in Anorexia Nervosa.Brain and behavior · 2025Review
- Sputum microbiota profiles of patients with rifampicin-resistant tuberculosis during the intensive-phase treatment.BMC microbiology · 2025Article
- Gut microbiota in infants with food protein enterocolitis.Pediatric research · 2025Article
- Unraveling the Microbiome-Human Body Axis: A Comprehensive Examination of Therapeutic Strategies, Interactions and Implications.International journal of molecular sciences · 2024Review
- How Microbiomes Affect Skin Aging: The Updated Evidence and Current Perspectives.Life (Basel, Switzerland) · 2022Review
- Prebiotic Potential of Dietary Beans and Pulses and Their Resistant Starch for Aging-Associated Gut and Metabolic Health.Nutrients · 2022Review
- Article
- Antidiabetic Effects ofNutrients · 2022Article
- Centenarian-SourcedNutrients · 2022Article
- Evaluating the beneficial effects of dietary restrictions: A framework for precision nutrigeroscience.Cell metabolism · 2021Review
- Article
- Article
- Whole Fruits and Fruit Fiber Emerging Health Effects.Nutrients · 2018Review
- Longevity extension in Drosophila through gut-brain communication.Scientific reports · 2018Article
- (Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease.Microbiome · 2017Review
- Targeting glucose metabolism for healthy aging.Nutrition and healthy aging · 2016Review
- Human gut microbiota and healthy aging: Recent developments and future prospective.Nutrition and healthy aging · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dietary resistant starch impact on intestinal microbiome and improving healthspan is the topic of this review. In the elderly population, dietary fiber intake is lower than recommended. Dietary resistant starch as a source of fiber produces a profound change in gut microbiota and fermentation in animal models of aging. Dietary resistant starch has the potential for improving healthspan in the elderly through multiple mechanisms as follows: (1) enhancing gut microbiota profile and production of short-chain fatty acids, (2) improving gut barrier function, (3) increasing gut peptides that are important in glucose homeostasis and lipid metabolism, and (4) mimicking many of the effects of caloric restriction including upregulation of genes involved in xenobiotic metabolism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.