Evidence map›Paper›PMID 26371050›Full record

ReviewJournal of clinical medicine2015

Non-Proteinuric Diabetic Nephropathy.

Nicolas Roberto Robles, Juan Villa, Roman Hernandez Gallego

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05021705 (Non Diabetic Causes of Chronic Kidney Disease in Type 2 Diabetic Patients), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05021705 completednot on this mapstarted 2016, after this paper: background citation

Non Diabetic Causes of Chronic Kidney Disease in Type 2 Diabetic Patients

Typeobservational_patient_registrySponsorAssiut UniversityRan2016 to 2020Enrolled60ConditionsDiabetic Kidney Disease
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Evolving spectrum of diabetic nephropathy.World journal of diabetes · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicolas Roberto RoblesCátedra de Riesgo Vascular, Facultad de Medicina, Universidad de Salamanca, Salamanca 37007, Spain. nrrobles@yahoo.es.
Juan VillaServicio de Nefrologia, Hospital Infanta Cristina, Badajoz 06070, Spain. jvilla_19@hotmail.com.
Roman Hernandez GallegoServicio de Nefrologia, Hospital Infanta Cristina, Badajoz 06070, Spain. romanhg78@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic nephropathy patients traditionally show significant macroalbuminuria prior to the development of renal impairment. However, this clinical paradigm has recently been questioned. Epidemiological surveys confirm that chronic kidney disease (CKD) diagnosed by a low glomerular filtration rate (GFR) is more common in diabetic patients than in the non-diabetic population but a low number of patients had levels of proteinuria above that which traditionally defines overt diabetic nephropathy (>500 mg/g). The large number of patients with low levels of proteinuria suggests that the traditional clinical paradigm of overt diabetic nephropathy is changing since it does not seem to be the underlying renal lesion in most of diabetic subjects with CKD.

Indexed as

chronic kidney diseasediabetes mellitusmicroalbuminuriaproteinuria

Identifiers

PMID26371050
PMCPMC4600158

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.